Opioid treatment for neonatal opioid withdrawal syndrome: current challenges and future approaches

BT McPhail, C Emoto, D Butler… - The Journal of …, 2021 - Wiley Online Library
Chronic intrauterine exposure to psychoactive drugs often results in neonatal opioid
withdrawal syndrome (NOWS). When nonpharmacologic measures are insufficient in …

Pharmacotherapy of neonatal opioid withdrawal syndrome: a review of pharmacokinetics and pharmacodynamics

MW van Hoogdalem, BT McPhail, D Hahn… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Neonatal opioid withdrawal syndrome (NOWS) often arises in infants born to
mothers who used opioids during pregnancy. Morphine, methadone, and buprenorphine are …

[HTML][HTML] Neonatal opioid withdrawal syndrome: a review of the science and a look toward the use of buprenorphine for affected infants

LA Devlin, LW Young, WK Kraft, EM Wachman… - Journal of …, 2022 - nature.com
Neonates born to mothers taking opioids during pregnancy are at risk for neonatal opioid
withdrawal syndrome (NOWS), for which there is no recognized standard approach to care …

Clinical pharmacology and dosing regimen optimization of neonatal opioid withdrawal syndrome treatments

F Tang, CM Ng, HS Bada… - Clinical and Translational …, 2021 - Wiley Online Library
In this paper, we review the management of neonatal opioid withdrawal syndrome (NOWS)
and clinical pharmacology of primary treatment agents in NOWS, including morphine …

[PDF][PDF] Neonatal Opioid Withdrawal Syndrome: A Developmental Care Approach.

L Piccotti, B Voigtman, R Vongsa, EM Nellhaus… - Neonatal …, 2019 - academia.edu
Tens of thousands of infants are impacted yearly by prenatal opioid exposure. The term
neonatal opioid withdrawal syndrome (NOWS) is now replacing the more familiar term …

Factors associated with the need for pharmacological management of neonatal opioid withdrawal syndrome

LF Scott, V Guilfoy, JM Duwve… - Advances in Neonatal …, 2020 - journals.lww.com
Background: Neonatal opioid withdrawal syndrome (NOWS) is a significant and growing
health problem that affects more than 23,000 infants annually, with an estimated hospital …

[HTML][HTML] Buprenorphine vs. morphine: impact on neonatal opioid withdrawal syndrome (NOWS) outcomes in a single center retrospective study

S Anbalagan, V Anderson, MT Favara, D Stark… - Journal of …, 2024 - nature.com
Objectives To compare clinical outcomes for infants with neonatal opioid withdrawal
syndrome (NOWS) treated with buprenorphine or morphine. Study design Retrospective …

Potential problems and solutions of opioid-based treatment in neonatal opioid withdrawal syndrome (NOWS): a scoping review protocol

S Mills-Huffnagle, JE Nyland - BMJ open, 2023 - bmjopen.bmj.com
Introduction Rates of neonatal opioid withdrawal syndrome (NOWS) have paralleled the rise
of opioid use during pregnancy. While short-term phenotypic symptoms of NOWS are well …

Advances in the care of infants with prenatal opioid exposure and neonatal opioid withdrawal syndrome

M Mascarenhas, EM Wachman, I Chandra, R Xue… - …, 2024 - publications.aap.org
A significant number of advances have been made in the last 5 years with respect to the
identification, diagnosis, assessment, and management of infants with prenatal opioid …

Neonatal opioid withdrawal syndrome

MB Sutter, L Leeman, A Hsi - Obstetrics and Gynecology …, 2014 - obgyn.theclinics.com
Neonates who have had in utero exposures from maternal substance abuse can experience
central nervous system effects of the drugs, including drug toxicity and withdrawal. Neonatal …