Osteoarthritis is a multifactorial disease characterized by cartilage degeneration, while
cartilage progenitor/stem cells (CPCs) are responsible for endogenous cartilage repair …

Cartilage progenitor/stem cells (CPCs) are promising seed cells for cartilage regeneration,
but their fate changes and regulatory mechanisms in osteoarthritis (OA) pathogenesis …

Osteoarthritis, also known as degenerative arthritis or degenerative joint disease, causes
pain and disability worldwide. Cartilage regeneration is key to finding a cure for this disease …

Osteoarthritis (OA) is an age-related musculoskeletal disease that results in pain and
functional disability. Stem cell therapy has been considered as a promising treatment for OA …

Mechanical overloading can promote cartilage senescence and osteoarthritis (OA)
development, but its impact on synovial macrophages and the interaction between …

Osteoarthritis (OA) is a progressive degeneration of articular cartilage with involvement of
synovial membrane, and subchondral bone. Recently, cell-based therapies, including the …

Osteoarthritis (OA) is a highly prevalent and debilitating joint disorder characterized by the
degeneration of articular cartilage. However, no effective medical therapy has been found …

Background Due to the unclear pathogenesis of osteoarthritis (OA), effective treatment for
this ailment is presently unavailable. Accumulating evidence points to chondrocyte …

Objective We evaluated the ability of miR-379-5p to influence the proliferation of
osteoarthritis chondrocytes and elucidated the regulatory mechanism of miR-379-5p in …

Excessive subchondral angiogenesis is a key pathological feature of osteoarthritis (OA), as it
alters the balance of subchondral bone remodeling and causes progressive cartilage …