Major depressive disorder is a serious mental disorder that profoundly affects an individual's
quality of life. Although the aetiologies underlying this disorder remain unclear, an …

Major depressive disorder (MDD) will affect one out of every five people in their lifetime and
is the leading cause of disability worldwide. Nevertheless, mechanisms associated with the …

In order to understand the molecular changes underlying major depression animal models
are needed. The best animal model of depression simulates the etiology and replicates …

Major depression is a complex psychiatric disorder characterized by affective, cognitive, and
physiological impairments that lead to maladaptive behavior. The high lifetime prevalence of …

Simple Summary Scientists use animal models to study the mechanisms of human diseases
and find new drugs to treat them. Chronic Unpredictable Mild Stress is the best animal …

Major depressive disorder (MDD) is a severe illness imposing an increasing social and
economic burden worldwide. Numerous rodent models have been developed to investigate …

Major depression disorder (MDD) is a debilitating mental illness with significant morbidity
and mortality. Despite the growing number of studies that have emerged, the precise …

Depression is one of the leading causes of disability and a significant health-concern
worldwide. Much of our current understanding on the pathogenesis of depression and the …

Major depressive disorder (MDD) is a chronic, recurrent, and severe psychiatric disorder
with high mortality and medical comorbidities. Stress‐related pathways have been directly …

Rodent models are an indispensable tool for studying etiology and progress of depression.
Since interrelated systems of neurotrophic factors and cytokines comprise major regulatory …