To determine whether bronchoconstriction can be mediated via the tachykinin NK3
receptors, isolated guinea pig lungs were challenged with the exogenous tachykinin NK3 …

The major pulmonary effects of tachykinins, including bronchoconstriction, are mediated by
activation of both neurokinin-1 (NK1) and neurokinin-2 (NK2) receptors. In guinea-pigs …

The aim of this study was to determine whether neurokinin B (NKB) or specific agonists of
tachykinin NK3 receptors,[MePhe7] NKB and senktide, were able to induce airway …

In vivo anesthetized guinea pigs were used to investigate the effect of tachykinin NK1-and
NK2-receptor antagonists, as a single dose or in combination, against hyperventilation …

On human small isolated bronchi (diameter< 1 mm), but not on larger bronchi (diameter 3-5
mm), substance P (SP) and specific tachykinin SP-preferring neurokinin (NK1) receptor …

1 NK1 and NK2 tachykinin receptors were characterized in guinea‐pig and rat
bronchopulmonary systems and in the vasculature of the rat by use of radioligand binding …

Tachykinins produce concentration-dependent contraction of the human isolated bronchus
by stimulation of receptors that belong to the NK2 type. The aim of this study was to …

We have investigated the antibronchoconstrictor activity of a novel glycosylated bicyclic
peptide tachykinin NK2 receptor antagonist, MEN 11420 c {[(β-d-GlcNAc) Asn-Asp-Trp-Phe …

Tachykinins have been implicated as important mediators of asthma. This study used
neurokinin A (NKA) and substance P (SP) to evaluate the effect of tachykinins on airway …

Experiments were performed to characterize the pharmacology of SCH 206272 [(R, R)-1′[5-
[(3, 5-dichlorobenzoyl) methylamino]-3-(3, 4-dichlorophenyl)-4 (Z)-(methoxyimino) pentyl]-N …