Injury to the spinal cord causes transection of axon fibers and neural cell death, resulting in
disruption of the neural network and severe functional loss. Reconstruction of the damaged …

Spinal cord injuries (SCIs) can lead to significant neurological deficits and lifelong disability,
with far-reaching physical, psychological, and economic consequences for affected …

Cell-based transplantation strategies are inherently combination therapies, as they may
mediate spinal cord repair via trophic or phenotypic mechanisms. The growth factor …

Spinal cord injury (SCI), resulting in para-and tetraplegia caused by the partial or complete
disruption of descending motor and ascending sensory neurons, represents a complex …

Spinal cord injury (SCI) invariably results in the loss of neurons and axonal degeneration at
the lesion site, leading to permanent paralysis and loss of sensation. There has been no …

Stem cell medicine has led to functional recovery in the acute-to-subacute phase of spinal
cord injury (SCI), but not yet in the chronic phase, during which various molecular …

✓ The development of an acute traumatic spinal cord injury (SCI) inevitably leads to a
complex cascade of ischemia and inflammation that results in significant scar tissue …

Spinal cord injury is a chronic and debilitating neurological condition that is currently being
managed symptomatically with no real therapeutic strategies available. Even though there is …

Over time, various treatment modalities for spinal cord injury have been trialed, including
pharmacological and nonpharmacological methods. Among these, replacement of the …

Basic science advances in spinal cord injury and regeneration research have led to a variety
of novel experimental therapeutics designed to promote functionally effective axonal …