On the viability and potential value of stem cells for repair and treatment of central neurotrauma: overview and speculations

S Wu, KT FitzGerald, J Giordano - Frontiers in Neurology, 2018 - frontiersin.org
Central neurotrauma, such as spinal cord injury or traumatic brain injury, can damage critical
axonal pathways and neurons and lead to partial to complete loss of neural function that is …

Stem cells and spinal cord injury repair

S Karimi-Abdolrezaee, E Eftekharpour - … Biology of the Spine and Spinal …, 2012 - Springer
Spinal cord injury (SCI) has remained a challenging area for scientists and clinicians due to
the adverse and complex nature of its pathobiology. To date, clinical therapies for …

Therapeutical strategies for spinal cord injury and a promising autologous astrocyte-based therapy using efficient reprogramming techniques

H Yang, C Liu, CY Wang, Q Zhang, J An, L Zhang… - Molecular …, 2016 - Springer
Spinal cord injury (SCI) is a traumatic event resulting in disturbances to normal sensory,
motor, or autonomic functions, which ultimately impacts a patient's physical, psychological …

Stem cell-based treatments for spinal cord injury

LA Wyatt, HS Keirstead - Progress in brain research, 2012 - Elsevier
Cell replacement strategies hold great promise for the treatment of central nervous system
injuries and degenerative diseases. The advancement of stem cell therapies has proven to …

Neural stem cells for spinal cord repair

B Sandner, P Prang, FJ Rivera, L Aigner, A Blesch… - Cell and tissue …, 2012 - Springer
Spinal cord injury (SCI) causes the irreversible loss of spinal cord parenchyma including
astroglia, oligodendroglia and neurons. In particular, severe injuries can lead to an almost …

[HTML][HTML] Advanced approaches to regenerate spinal cord injury: the development of cell and tissue engineering therapy and combinational treatments

J Saremi, N Mahmoodi, M Rasouli, FE Ranjbar… - Biomedicine & …, 2022 - Elsevier
Spinal cord injury (SCI) is a central nervous system (CNS) devastate event that is commonly
caused by traumatic or non-traumatic events. The reinnervation of spinal cord axons is …

Research progress of endogenous neural stem cells in spinal cord injury

YT Wang, H Yuan - ibrain, 2022 - Wiley Online Library
Spinal cord injury (SCI) is a severe disabling disease, which mainly manifests as
impairments of sensory and motor functions, sexual function, bladder and intestinal …

Concise review: Spinal cord injuries: how could adult mesenchymal and neural crest stem cells take up the challenge?

V Neirinckx, D Cantinieaux, C Coste, B Rogister… - Stem …, 2014 - academic.oup.com
Since several years, adult/perinatal mesenchymal and neural crest stem cells have been
widely used to help experimental animal to recover from spinal cord injury. More …

Transplant mediated repair of the central nervous system: an imminent solution?

A Lakatos, RJM Franklin - Current opinion in neurology, 2002 - journals.lww.com
Recent advances largely involve experimental refinements of existing approaches and the
emergent application of stem cell biology to overcome spinal cord injury. While most …

Cellular transplantation-based evolving treatment options in spinal cord injury

M Wu, H Yuan, K Li, DL Qiu - Cell biochemistry and biophysics, 2015 - Springer
Spinal cord injury (SCI) often represents a condition of permanent neurologic deficit. It has
been possible to understand and delineate the mechanisms contributing to loss of function …