[HTML][HTML] Strategies and prospects of effective neural circuits reconstruction after spinal cord injury
B Yang, F Zhang, F Cheng, L Ying, C Wang, K Shi… - Cell Death & …, 2020 - nature.com
Due to the disconnection of surviving neural elements after spinal cord injury (SCI), such
patients had to suffer irreversible loss of motor or sensory function, and thereafter enormous …
patients had to suffer irreversible loss of motor or sensory function, and thereafter enormous …
The combined strategy of mesenchymal stem cells and tissue-engineered scaffolds for spinal cord injury regeneration
P Bramanti, E Mazzon - … and Therapeutic Medicine, 2017 - spandidos-publications.com
Spinal cord injury (SCI) is a traumatic lesion that can result in the loss of motor or sensory
neurons. Stem cell (SC)‑based therapies have been demonstrated to promote neuronal …
neurons. Stem cell (SC)‑based therapies have been demonstrated to promote neuronal …
[HTML][HTML] Current concepts of stem cell therapy for chronic spinal cord injury
H Suzuki, T Sakai - International Journal of Molecular Sciences, 2021 - mdpi.com
Chronic spinal cord injury (SCI) is a catastrophic condition associated with significant
neurological deficit and social and financial burdens. It is currently being managed …
neurological deficit and social and financial burdens. It is currently being managed …
Roles of mesenchymal stem cells in spinal cord injury
J Qu, H Zhang - Stem cells international, 2017 - Wiley Online Library
Spinal cord injury (SCI) represents one of the most complicated and heterogeneous
pathological processes of central nervous system (CNS) impairments, which is still beyond …
pathological processes of central nervous system (CNS) impairments, which is still beyond …
Neuronal repair and replacement in spinal cord injury
FM Bareyre - Journal of the neurological sciences, 2008 - Elsevier
Spinal cord injury (SCI) often induces loss of motor and/or sensory function below the level
of injury. While deficits persist in complete lesions, partial lesions of the spinal cord can be …
of injury. While deficits persist in complete lesions, partial lesions of the spinal cord can be …
[HTML][HTML] Activating endogenous neurogenesis for spinal cord injury repair: recent advances and future prospects
H Yu, S Yang, H Li, R Wu, B Lai, Q Zheng - Neurospine, 2023 - ncbi.nlm.nih.gov
After spinal cord injury (SCI), endogenous neural stem cells are activated and migrate to the
injury site where they differentiate into astrocytes, but they rarely differentiate into neurons. It …
injury site where they differentiate into astrocytes, but they rarely differentiate into neurons. It …
Combination of multifaceted strategies to maximize the therapeutic benefits of neural stem cell transplantation for spinal cord repair
DH Hwang, HM Kim, YM Kang, IS Joo… - Cell …, 2011 - journals.sagepub.com
Neural stem cells (NSCs) possess therapeutic potentials to reverse complex pathological
processes following spinal cord injury (SCI), but many obstacles remain that could not be …
processes following spinal cord injury (SCI), but many obstacles remain that could not be …
[HTML][HTML] An insight into the prospects and drawbacks of stem cell therapy for spinal cord injuries: ongoing trials and future directions
SI Khan, N Ahmed, K Ahsan, M Abbasi, R Maugeri… - Brain Sciences, 2023 - mdpi.com
Spinal cord injury (SCI) is a devastating neurological disorder that has a substantial
detrimental impact on a person's quality of life. The estimated global incidence of SCI is 40 …
detrimental impact on a person's quality of life. The estimated global incidence of SCI is 40 …
Human stem cell–derived neurons and neural circuitry therapeutics: Next frontier in spinal cord injury repair
MB Paredes-Espinosa… - Experimental Biology and …, 2022 - journals.sagepub.com
Spinal cord injury (SCI) remains a life-altering event that devastates those injured and the
families that support them. Numerous laboratories are engaged in preclinical and clinical …
families that support them. Numerous laboratories are engaged in preclinical and clinical …
[HTML][HTML] Stem cells for spinal cord regeneration: Current status
Background: Nearly 11,000 cases of spinal cord injury (SCI) are reported in the United
States annually. Current management options give a median survival time of 38 years; …
States annually. Current management options give a median survival time of 38 years; …