Cystic fibrosis (CF) is caused by a nonfunctional chloride and bicarbonate ion channel (CF
transmembrane regulator [CFTR]), but the link to the phenomenon of stagnant mucus is not …

The mechanisms underlying mucus-associated pathologies in cystic fibrosis (CF) remain
obscure. However, recent studies indicate that CF transmembrane conductance regulator …

Background Cystic fibrosis (CF, mucoviscidosis) is caused by mutations in the gene
encoding CF transmembrane conductance regulator (CFTR), which is a chloride and …

Mucus pathology in cystic fibrosis (CF) has been known for as long as the disease has been
recognized and is sometimes called mucoviscidosis. The disease is marked by mucus …

The gene that encodes for the cystic fibrosis transmembrane regulator protein (CFTR) was
identified in 1989, yet major pathophysiologic questions remain unanswered. There is …

The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP and cGMP-
regulated chloride channel critical to the regulation of intestinal fluid, chloride, and …

Our current understanding of cystic fibrosis (CF) has revealed that the biophysical properties
of mucus play a considerable role in the pathogenesis of the disease in view of the fact that …

Cystic fibrosis (CF) is a common, life-threatening, multisystemic, autosomal recessive
disorder. In the last few years, giant steps have been made with regard to the understanding …

The clinical manifestations of cystic fibrosis (CF) result from dysfunction of the cystic fibrosis
transmembrane regulator protein (CFTR). The majority of people with CF have a limited life …

Cystic fibrosis (CF) is a recessive genetic disease caused by mutations in a gene encoding
a protein called Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). The CFTR …