Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii

M Ud-Din, A Albutti, A Ullah, S Ismail, S Ahmad… - International Journal of …, 2022 - mdpi.com
Antibiotic resistance (AR) is the result of microbes' natural evolution to withstand the action
of antibiotics used against them. AR is rising to a high level across the globe, and novel …

Pangenome and immuno-proteomics analysis of Acinetobacter baumannii strains revealed the core peptide vaccine targets

A Hassan, A Naz, A Obaid, RZ Paracha, K Naz… - BMC genomics, 2016 - Springer
Background Acinetobacter baumannii has emerged as a significant nosocomial pathogen
during the last few years, exhibiting resistance to almost all major classes of antibiotics …

Chimeric vaccine designs against Acinetobacter baumannii using pan genome and reverse vaccinology approaches

F Shahid, T Zaheer, ST Ashraf, M Shehroz, F Anwer… - Scientific reports, 2021 - nature.com
Abstract Acinetobacter baumannii (A. baumannii), an opportunistic, gram-negative
pathogen, has evoked the interest of the medical community throughout the world because …

[HTML][HTML] Putative novel B-cell vaccine candidates identified by reverse vaccinology and genomics approaches to control Acinetobacter baumannii serotypes

S Beiranvand, A Doosti, SA Mirzaei - Infection, Genetics and Evolution, 2021 - Elsevier
In the last decade, Multi-drug resistance (MDR)-associated infections of Acinetobacter
baumannii have grown worldwide. A cost-effective preventative strategy against this …

In-Silico Vaccine Design Based on a Novel Vaccine Candidate Against Infections Caused by Acinetobacter baumannii

K Khalid, S Irum, SR Ullah, S Andleeb - International journal of peptide …, 2022 - Springer
Acinetobacter baumannii is notorious for causing serious infections of the skin, lungs, soft
tissues, bloodstream, and urinary tract. Despite the overwhelming information available so …

Designing of multi-epitope peptide vaccine against Acinetobacter baumannii through combined immunoinformatics and protein interaction–based approaches

J Dey, SR Mahapatra, PK Singh… - Immunologic …, 2023 - Springer
Acinetobacter baumannii is one of the major pathogenic ESKAPE bacterium, which is
responsible for about more than 722,000 cases in a year, globally. Despite the alarming …

Identification of Novel Vaccine Candidates against Multidrug-Resistant Acinetobacter baumannii

DG Moriel, SA Beatson, DJ Wurpel, J Lipman… - PloS one, 2013 - journals.plos.org
Acinetobacter baumannii is an emerging opportunistic bacterium associated with
nosocomial infections in intensive care units. The alarming increase in infections caused by …

Antibiotic Resistance Determinant-Focused Acinetobacter baumannii Vaccine Designed Using Reverse Vaccinology

Z Ni, Y Chen, E Ong, Y He - International journal of molecular sciences, 2017 - mdpi.com
As one of the most influential and troublesome human pathogens, Acinetobacter baumannii
(A. baumannii) has emerged with many multidrug-resistant strains. After collecting 33 …

Identification of novel vaccine candidates against Acinetobacter baumannii using reverse vaccinology

MH Chiang, WC Sung, SP Lien, YZ Chen… - Human vaccines & …, 2015 - Taylor & Francis
Acinetobacter baumannii (Ab) is a global emerging bacterium causing nosocomial infections
such as pneumonia, meningitis, bacteremia and soft tissue infections especially in intensive …

Immunoprotective Efficacy of Acinetobacter baumannii Outer Membrane Protein, FilF, Predicted In silico as a Potential Vaccine Candidate

R Singh, N Garg, G Shukla, N Capalash… - Frontiers in …, 2016 - frontiersin.org
Acinetobacter baumannii is emerging as a serious nosocomial pathogen with multidrug
resistance that has made it difficult to cure and development of efficacious treatment against …