Noscapine is a non-narcotic alkaloid known to display anti-cancer activity against a wide
variety of tumors. Since plasma proteins play the central role in drug transport and targeting …

Investigation of the interaction of hemoglobin (Hb) with therapeutic agents may be useful
from three perspectives. First, there are a few therapeutic agents targeting precisely Hb …

Noscapine hydrochloride (Nos), an opium derived anticancer agent manifests therapeutic
applications and is compliant to beneficial modifications. In this paper, we study its …

Synthetic dyes are a very efficient class of dyes that are ingested or come into contact with
the skin from numerous sources (cosmetics, textiles, leather, paper, and drugs). An important …

Protein–ligand interaction studies are useful to determine the molecular mechanism of the
binding phenomenon, leading to the establishment of the structure–function relationship …

Abstract Bromo-Noscapine (BrNs) is a tubulin-binding cytotoxic agent with significant activity
against breast and lung cancer. The mechanistic interaction insight into the binding of …

The association of a putative bioactive alkaloid nitidine (NIT) with blood protein bovine
hemoglobin (BHb) was investigated by employing various biophysical and molecular …

Binding of the well‐known antibiotic drug sulfamethazine (SMZ) with tetrameric heme
protein, hemoglobin (Hb), was studied using spectroscopic, calorimetric and molecular …

The interaction between synthesized heterocyclic benzene sulfonamide compounds, N-(7-
benzyl-56-biphenyl-2m-tolyl-7H-pyrrolo [23-d] pyrimidine–4–yl)-benzene sulfonamide …

Hemoglobin, a homodimeric globular protein, is found predominantly in red blood cells and
in a small amount in blood plasma. Along with binding to certain native molecules, it also …