Heterogenous patterns of sensory dysfunction in postherpetic neuralgia suggest multiple pathophysiologic mechanisms

M Pappagallo, AL Oaklander… - The Journal of the …, 2000 - pubs.asahq.org
Background Postherpetic neuralgia (PHN) is considered by some investigators to be
predominantly a deafferentation-type central pain syndrome; others suggest that activity of …

The neuropathic pain scales

HT Benzon - Regional anesthesia and pain medicine, 2005 - search.proquest.com
Neuropathic pain is defined as pain initiated or caused by a primary lesion or dysfunction of
the nervous system. Syndromes such as postherpetic neuralgia, complex regional pain …

Postherpetic neuralgia: irritable nociceptors and deafferentation

HL Fields, M Rowbotham, R Baron - Neurobiology of disease, 1998 - Elsevier
Postherpetic neuralgia (PHN) is a common and often devastatingly painful condition. It is
also one of the most extensively investigated of the neuropathic pains. Patients with PHN …

Association between pain, central sensitization and anxiety in postherpetic neuralgia

T Schlereth, A Heiland, M Breimhorst… - … journal of pain, 2015 - Wiley Online Library
Background In postherpetic neuralgia (PHN), dorsal root ganglia neurons are damaged.
According to the proposed models, PHN pain might be associated with nociceptive …

Post-herpetic neuralgia: the relation of pain complaint, sensory disturbance and skin temperature

MC Rowbotham, HL Fields - Pain, 1989 - Elsevier
Twelve otherwise healthy patients with longstanding postherpetic neuralgia (PHN) were
prospectively studied using clinical examination, infrared thermography and response to …

The relationship of pain, allodynia and thermal sensation in post-herpetic neuralgia

MC Rowbotham, HL Fields - Brain, 1996 - academic.oup.com
In the syndrome of post-herpetic neuralgia (PHN), the nature of the sensory disturbance and
its relationship both to the severity and cause of the pain is controversial. To address these …

Basal heat pain thresholds predict opioid analgesia in patients with postherpetic neuralgia

RR Edwards, JA Haythornthwaite, P Tella… - The Journal of the …, 2006 - pubs.asahq.org
Background A variety of analgesics have been studied in the treatment of postherpetic
neuralgia, with several medications demonstrating some degree of efficacy. However …

Is postherpetic neuralgia more than one disorder?

MC Rowbotham, KL Petersen, HL Fields - Pain Forum, 1998 - Elsevier
Acute herpes zoster is a highly stereotyped condition of viral recrudescence producing
inflammation in a dorsal root ganglion, a segmental vesicular rash, and pain. The long-term …

Pathophysiology of pain in postherpetic neuralgia: a clinical and neurophysiological study

A Truini, F Galeotti, M Haanpaa, R Zucchi, A Albanesi… - Pain, 2008 - Elsevier
Postherpetic neuralgia is an exceptionally drug-resistant neuropathic pain. To investigate
the pathophysiological mechanisms underlying postherpetic neuralgia we clinically …

Impaired modulation of pain in patients with postherpetic neuralgia

G Pickering, B Pereira, E Dufour, S Soule… - Pain Research and …, 2014 - hindawi.com
BACKGROUND: The efficiency of inhibitory pain descending pathways (evaluated using
conditioned pain modulation [CPM]) has not been studied in postherpetic neuralgia (PHN) …