Hydrogenases are metalloenzymes subdivided into two classes that contain iron-sulfur
clusters and catalyze the reversible oxidation of hydrogen gas (H 2⇆ 2H++ 2e−). Two metal …

Hydrogenases catalyze the reversible conversion of molecular hydrogen to protons and
electrons via a heterolytic splitting mechanism. The active sites of [NiFe] hydrogenases …

Hydrogenases (H 2 ases) are metalloproteins. The great majority of them contain iron-sulfur
clusters and two metal atoms at their active center, either a Ni and an Fe atom, the [NiFe]-H 2 …

The activation of molecular hydrogen is of interest both from a chemical and biological
viewpoint. The covalent bond of H2 is strong (436 kJ mol− 1). Its cleavage is catalyzed by …

Abstract The [FeFe]-and [NiFe]-hydrogenases catalyze the formal interconversion between
hydrogen and protons and electrons, possess characteristic non-protein ligands at their …

Hydrogenases are enzymes that catalyze the reversible conversion of hydrogen into protons
and electrons with high activity and efficiency. Recently, it was discovered that semisynthetic …

Hydrogenases are nature's catalysts designed to extract protons from molecular hydrogen
(H2) thereby forming a reactive hydride species (H−). Those enzymes capable of catalyzing …

Abstract [NiFe] hydrogenases are well-characterized enzymes that have a key function in the
H 2 metabolism of various microorganisms. In the recent years a subfamily of [NiFe] …

Most methanogenic archaea reduce CO2 with H2 to CH4. For the activation of H2, they use
different [NiFe]-hydrogenases, namely energy-converting [NiFe]-hydrogenases …

Hydrogenases represent a heterogeneous group of enzymes consisting of three
evolutionary unrelated classes, ie [NiFe],[FeFe] and [Fe] hydrogenases. They allow the uni …