Reverse vaccinology: the pathway from genomes and epitope predictions to tailored recombinant vaccines
In this chapter, we review the computational approaches that have led to a new generation
of vaccines in recent years. There are many alternative routes to develop vaccines based on …
of vaccines in recent years. There are many alternative routes to develop vaccines based on …
An update on “reverse vaccinology”: The pathway from genomes and epitope predictions to tailored, recombinant vaccines
In this chapter, we review the computational approaches that have led to a new generation
of vaccines in recent years. There are many alternative routes to develop vaccines based on …
of vaccines in recent years. There are many alternative routes to develop vaccines based on …
Reverse vaccinology
R Rappuoli - Current opinion in microbiology, 2000 - Elsevier
Biochemical, serological and microbiological methods have been used to dissect pathogens
and identify the components useful for vaccine development. Although successful in many …
and identify the components useful for vaccine development. Although successful in many …
Developing vaccines in the era of genomics: a decade of reverse vaccinology
KL Seib, X Zhao, R Rappuoli - Clinical Microbiology and …, 2012 - Wiley Online Library
Clin Microbiol Infect 2012; 18 (Suppl. 5): 109–116 Abstract Vaccines have a significant
impact on public health, and vaccinology in the era of genomics is taking advantage of new …
impact on public health, and vaccinology in the era of genomics is taking advantage of new …
An overview of progress from empirical to rational design in modern vaccine development, with an emphasis on computational tools and immunoinformatics …
Vaccination remains the most effective strategy for preventing and controlling infectious
diseases. Numerous conventional vaccines, especially live attenuated, inactivated (killed) …
diseases. Numerous conventional vaccines, especially live attenuated, inactivated (killed) …
Reverse vaccinology
R Moxon, PA Reche, R Rappuoli - Frontiers in immunology, 2019 - frontiersin.org
For many, the semantics of the term “reverse vaccinology” may be puzzling. Literally, it
implies a complete change of direction or action in the study of vaccines. The non-obvious …
implies a complete change of direction or action in the study of vaccines. The non-obvious …
The promise of reverse vaccinology
AI Heinson, CH Woelk, ML Newell - International health, 2015 - academic.oup.com
Reverse vaccinology (RV) is a computational approach that aims to identify putative vaccine
candidates in the protein coding genome (proteome) of pathogens. RV has primarily been …
candidates in the protein coding genome (proteome) of pathogens. RV has primarily been …
[引用][C] Microbial vaccine design: the reverse vaccinology approach
R Rosini, MA Barocchi… - Development of Vaccines …, 2011 - Wiley Online Library
Microbial Vaccine Design: The Reverse Vaccinology Approach Page 1 PART 1 IMMUNOGEN
DESIGN Page 2 1 MICROBIAL VACCINE DESIGN: THE REVERSE VACCINOLOGY …
DESIGN Page 2 1 MICROBIAL VACCINE DESIGN: THE REVERSE VACCINOLOGY …
VacSol: a high throughput in silico pipeline to predict potential therapeutic targets in prokaryotic pathogens using subtractive reverse vaccinology
Background With advances in reverse vaccinology approaches, a progressive improvement
has been observed in the prediction of putative vaccine candidates. Reverse vaccinology …
has been observed in the prediction of putative vaccine candidates. Reverse vaccinology …
A guide to current methodology and usage of reverse vaccinology towards in silico vaccine discovery
SJ Goodswen, PJ Kennedy… - FEMS Microbiology …, 2023 - academic.oup.com
Reverse vaccinology (RV) was described at its inception in 2000 as an in silico process that
starts from the genomic sequence of the pathogen and ends with a list of potential protein …
starts from the genomic sequence of the pathogen and ends with a list of potential protein …