Liver fibrosis is the consequence of chronic liver injury of any etiology. When advanced,
fibrosis causes portal hypertension and liver insufficiency, and is a risk factor for developing …

The renin-angiotensin system (RAS) is involved in hepatic fibrosis. To date there is no
known effective treatment for hepatic fibrosis. Modulation of the RAS with angiotensin …

Hepatic fibrosis, which is characterized by progressive inflammation and deposition of
extracellular matrix components, is a common response to chronic liver disease. Hepatic …

Hepatic fibrosis is considered a common response to many chronic hepatic injuries. It is a
multifunctional process that involves several cell types, cytokines, chemokines and growth …

There is an increasing body of evidence to suggest that the RAS (renin–angiotensin system)
contributes to tissue injury and fibrosis in chronic liver disease. A number of studies have …

Liver fibrosis is caused by many chronic diseases. Liver injury results in activation of
collagen‐producing cells and excessive deposition of extracellular matrix proteins. This …

Recent studies have shown that the renin–angiotensin system (RAS) plays a pivotal role in
liver fibrosis. An intrahepatic RAS is expressed in chronically damaged livers, and …

Liver fibrosis affects over 100 million people in the world; it represents a multifactorial, fibro-
inflammatory disorder characterized by exacerbated production of extracellular matrix with …

Hepatic fibrosis is a complex mechanism defined by the net deposition of the extracellular
matrix (ECM) owing to liver injury caused by multiple etiologies such as viral hepatitis and …

Liver fibrosis occurs in response to any etiology of chronic liver injury including hepatitis B
and C, alcohol consumption, fatty liver disease, cholestasis, and autoimmune hepatitis …