Infants are born with immature immune systems, making it difficult for them to effectively
respond to the infectious pathogens encountered shortly after birth. Maternal antibody is …

Transplacentally-acquired antibodies are important for protection of infants in the early
months of life. Maternal antibodies may dampen the infant's primary antibody response to …

Neonates have an immature immune system, which cannot adequately protect against
infectious diseases. Early in life, immune protection is accomplished by maternal antibodies …

Many serious infectious diseases occur early in life; efficacious vaccination of neonates has
been a longstanding goal in both human and veterinary medicine. Efforts to immunize in the …

Presence of maternally-derived antibodies at time of immunization is known to often interfere
with active infant immunization, although with variable degrees of clinical significance. In …

During the last few decades, maternal immunization as a strategy to protect young infants
from infectious diseases has been increasingly recommended, yet some issues have …

The prevention of severe infectious diseases in children through immunization is a well-
recognized, beneficial, and cost-effective strategy worldwide. 17 Neonates and young …

The presence of maternally-derived antibodies at the time of immunization is known to
interfere frequently with active immunization, with variable levels of clinical significance …

With birth, the newborn is transferred from a quasi-sterile environment to the outside world.
At this time, the neonatal immune system is inexperienced and continuously subject to a …

Neonates are born with an immature immune system and rely on the transfer of immunity
from their mothers. Maternal antibodies are transferred via the placenta and breast milk …