The formation of severe scars still represents the result of the closure process of extended
and deep skin wounds. To address this issue, different bioengineered skin substitutes have …

Regenerative medicine and tissue engineering (TE) have experienced significant advances
in the development of in vitro engineered skin substitutes, either for replacement of lost …

The global volume of skin damage or injuries has major healthcare implications and,
accounts for about half of the world's annual expenditure in the healthcare sector. In the last …

The development and use of artificial skin in treating acute and chronic wounds has, over
the last 30 years, advanced from a scientific concept to a series of commercially viable …

Wound healing can be problematic in several clinical settings because of massive tissue
injury (burns), wound healing deficiencies (chronic wounds), or congenital conditions and …

Tissue engineered skin substitutes for wound healing have evolved tremendously over the
last couple of years. New advances have been made toward developing skin substitutes …

Chronic wounds occur as a consequence of a prolonged inflammatory phase during the
healing process, which precludes skin regeneration. Typical treatment for chronic wounds …

Skin protects the body from exogenous substances and functions as a barrier to fluid loss
and trauma. The skin comprises of epidermal, dermal and hypodermal layers, which mainly …

Tissue-engineered skin is a significant advance in the field of wound healing. It has mainly
been developed because of limitations associated with the use of autografts and allografts …

Extensive skin loss and chronic wounds are still a significant challenge to clinicians: even if
injured epidermis is normally able to self-renew, deep injuries can cause negative …