Nicotine directly induces endoplasmic reticulum stress response in rat placental trophoblast giant cells

MK Wong, AC Holloway, DB Hardy - Toxicological Sciences, 2016 - academic.oup.com
Nicotine exposure during pregnancy leads to placental insufficiency impairing both fetal and
neonatal development. Previous studies from our laboratory have demonstrated that in rats …

Safety of nicotine replacement therapy during pregnancy: a narrative review

M Morales-Suarez-Varela, BM Puig, L Kaerlev… - International Journal of …, 2022 - mdpi.com
Background: Smoking during pregnancy is a public health problem worldwide and the
leading preventable cause of fetal morbidity and mortality and obstetric disease. Although …

Critical review: nicotine for the fetus, the infant and the adolescent?

KH Ginzel, GS Maritz, DF Marks… - Journal of health …, 2007 - journals.sagepub.com
The recent expansion of Nicotine Replacement Therapy to pregnant women and children
ignores the fact that nicotine impairs, disrupts, duplicates and/or interacts with essential …

Smoking and preterm birth

R Ion, AL Bernal - Reproductive sciences, 2015 - journals.sagepub.com
Premature birth is a significant global problem and the leading cause of newborn deaths.
Tobacco smoking has been associated with premature birth for over 50 years. The …

Smoking during pregnancy: lessons learned from epidemiological studies and experimental studies using animal models

LC Abbott, UH Winzer-Serhan - Critical reviews in toxicology, 2012 - Taylor & Francis
Numerous epidemiological studies in the human population clearly indicate that smoking
while pregnant has deleterious effects on fetal development as well as long-term adverse …

If nicotine is a developmental neurotoxicant in animal studies, dare we recommend nicotine replacement therapy in pregnant women and adolescents?

TA Slotkin - Neurotoxicology and teratology, 2008 - Elsevier
Tobacco use in pregnancy is a leading cause of perinatal morbidity and contributes in major
ways to attention deficit hyperactivity disorder, conduct disorders and learning disabilities …

Developmental toxicity of nicotine: a transdisciplinary synthesis and implications for emerging tobacco products

LJ England, K Aagaard, M Bloch, K Conway… - Neuroscience & …, 2017 - Elsevier
While the health risks associated with adult cigarette smoking have been well described,
effects of nicotine exposure during periods of developmental vulnerability are often …

Prenatal cigarette smoke exposure: pregnancy outcome and gestational changes in plasma nicotine concentration, hematocrit, and carboxyhemoglobin in a newly …

S Farkas, J Hussein, RE Ariano, DS Sitar… - Toxicology and applied …, 2006 - Elsevier
Epidemiological studies support an association between perinatal cigarette smoke (CS)
exposure and a number of severe pre-and postnatal complications. However, the …

Melatonin ameliorates murine fetal oocyte meiotic dysfunction in F1 and F2 offspring caused by nicotine exposure during pregnancy

WX Liu, SJ Tan, YF Wang, L Li, XF Sun, J Liu… - Environmental …, 2020 - Elsevier
Although there is abundant evidence to demonstrate that maternal smoking during
pregnancy will harm the health of future generations, the impact of nicotine use by pregnant …

Comparison of nicotine exposure during pregnancy when smoking and abstinent with nicotine replacement therapy: systematic review and meta‐analysis

C Hickson, S Lewis, KA Campbell, S Cooper… - …, 2019 - Wiley Online Library
Background and aims Smoking during pregnancy is strongly associated with negative
pregnancy and perinatal outcomes. Some guidelines recommend nicotine replacement …