Background Chickens are susceptible to infection with a limited number of Influenza A
viruses and are a potential source of a human influenza pandemic. In particular, H5 and H7 …

The evolution of winged insects revolutionized terrestrial ecosystems and led to the largest
animal radiation on Earth. However, we still have an incomplete picture of the genomic …

Previous research revealed the induction of chicken USP18 (chUSP18) in the lungs of
chickens infected with highly pathogenic avian influenza viruses (HPAIVs). This activity was …

Protein regulation by ubiquitin has been extensively described in model organisms.
However, characterization of the ubiquitin machinery in disease vectors remains mostly …

An infectious bronchitis virus (IBV) with an unusual enteric tropism (CalEnt) was isolated
from a California broiler flock exhibiting runting-stunting syndrome. IBV was detected in the …

Cilia allowed our protistan ancestors to sense and explore their environment, avoid
predation, and capture bacterial prey. 1, 2, 3 Regulated ciliogenesis was likely critical for …

Motile cilia are ancient, evolutionarily conserved organelles whose dysfunction underlies
motile ciliopathies, a broad class of human diseases. Motile cilia contain myriad different …

Colonization and migration have a crucial effect on patterns of biodiversity, with disease
predicted to play an important role in these processes. However, evidence of the effect of …

Primary ciliary dyskinesia (PCD) is caused when defects of motile cilia lead to chronic
airway infections, male infertility, and situs abnormalities. Multiple causative PCD mutations …

WFDC2/HE4 encodes a poorly characterised secretory protein that shares structural
similarity with multifunctional host defence proteins through possession of two conserved …