[HTML][HTML] Comprehensive molecular characterization reveals genomic and transcriptomic subtypes of metastatic urothelial carcinoma
JA Nakauma-González, M Rijnders, J van Riet… - European urology, 2022 - Elsevier
Recent molecular characterization of primary urothelial carcinoma (UC) may guide future
clinical decision-making. For metastatic UC (mUC), a comprehensive molecular …
clinical decision-making. For metastatic UC (mUC), a comprehensive molecular …
[HTML][HTML] Molecular urothelial tumor cell subtypes remain stable during metastatic evolution
Urothelial cancer (UC) care is moving toward precision oncology. For tumor biology–driven
treatment of metastatic UC (mUC), molecular subtypes play a crucial role. However, it is not …
treatment of metastatic UC (mUC), molecular subtypes play a crucial role. However, it is not …
[HTML][HTML] Genomic distinctions between metastatic lower and upper tract urothelial carcinoma revealed through rapid autopsy
BACKGROUND Little is known about the genomic differences between metastatic lower
tract urothelial carcinoma (LTUC) and upper tract urothelial carcinoma (UTUC). We compare …
tract urothelial carcinoma (LTUC) and upper tract urothelial carcinoma (UTUC). We compare …
Collaborative study from the Bladder Cancer Advocacy Network for the genomic analysis of metastatic urothelial cancer
Abstract Urothelial Cancer-Genomic Analysis to Improve Patient Outcomes and Research
(NCT02643043), UC-GENOME, is a genomic analysis and biospecimen repository study in …
(NCT02643043), UC-GENOME, is a genomic analysis and biospecimen repository study in …
Metastasis and recurrence patterns in the molecular subtypes of urothelial bladder cancer
G Sjödahl, P Eriksson, K Holmsten… - … Journal of Cancer, 2024 - Wiley Online Library
Urothelial cancer of the urinary bladder frequently metastasizes to lymph‐nodes, lungs, liver
and bone. A taxonomy for molecular classification exists, but it is unknown if molecular …
and bone. A taxonomy for molecular classification exists, but it is unknown if molecular …
The evolution of metastatic upper tract urothelial carcinoma through genomic-transcriptomic and single-cell protein markers analysis
K Ohara, AF Rendeiro, B Bhinder, KW Eng… - Nature …, 2024 - nature.com
The molecular characteristics of metastatic upper tract urothelial carcinoma (UTUC) are not
well understood, and there is a lack of knowledge regarding the genomic and transcriptomic …
well understood, and there is a lack of knowledge regarding the genomic and transcriptomic …
[HTML][HTML] Molecular characterization of urothelial carcinoma of the bladder and upper urinary tract
JY Lee, K Kim, HH Sung, HG Jeon, BC Jeong… - Translational …, 2018 - Elsevier
PURPOSE: A better understanding of the molecular basis of urothelial carcinoma (UC) is
needed to refine the clinical decision-making process. METHODS AND MATERIALS: We …
needed to refine the clinical decision-making process. METHODS AND MATERIALS: We …
Advanced urothelial carcinoma: next-generation sequencing reveals diverse genomic alterations and targets of therapy
JS Ross, K Wang, RN Al-Rohil, T Nazeer… - Modern …, 2014 - nature.com
Although urothelial carcinoma (UC) of the urinary bladder generally portends a favorable
prognosis, metastatic tumors often follow an aggressive clinical course. DNA was extracted …
prognosis, metastatic tumors often follow an aggressive clinical course. DNA was extracted …
Characterization of metastatic urothelial carcinoma via comprehensive genomic profiling of circulating tumor DNA
BACKGROUND Biomarker‐guided clinical trials are increasingly common in metastatic
urothelial carcinoma (mUC), yet patients for whom contemporary tumor tissue is not …
urothelial carcinoma (mUC), yet patients for whom contemporary tumor tissue is not …
Comprehensive genomic profiling of upper tract urothelial carcinoma and urothelial carcinoma of the bladder identifies distinct molecular characterizations with …
Q Tang, W Zuo, C Wan, S Xiong, C Xu, C Yuan… - Frontiers in …, 2023 - frontiersin.org
Backgrounds Despite the genomic landscape of urothelial carcinomas (UC) patients,
especially those with UC of bladder (UCB), has been comprehensively delineated and …
especially those with UC of bladder (UCB), has been comprehensively delineated and …