• This double-blind, three-way crossover study measured the influence of β-blocker
treatment on drowsiness and mental test performance in older hypertensive patients and …

• The sedative effects of a relatively lipid-soluble and a water-soluble β-blocker were
compared in 20 male hypertensives, 30 to 60 years old. In a blinded, randomized, crossover …

This study examined the effects of atenolol and metoprolol on neuropsychologic functioning,
mood, sedation, and sleep. Following tapering of antihypertensive medication and a 3-wk …

Study objective: To test reports that beta blockers, particularly lipopbilic forms, impair
cognitive function and cause psychiatric disturbances. Design: Randomized, double-blind …

This study compared the effects of beta-blockers differing in degree of central nervous
system penetration on Type A behavior and cardiovascular reactivity to mental stress. Forty …

In this industrial-based study we compared the blood pressure (BP)-lowering effectiveness
of relaxation, a beta blocker, and the combined use of these two treatments in 47 untreated …

▪ Objective: To compare the effects of atenolol and nifedipine on mood and cognitive
function in elderly hypertensive patients.▪ Design: Randomized, double-blind, crossover …

• Fifty-five studies of cognitive side effects of β-blockers were reviewed. Many of the studies
were limited by small sample size, use of drugs out of the range of normal administration …

Antihypertensive medications are all associated with adverse reactions, and the elderly
patient may be particularly sensitive. In a large longitudinal follow up study in an aged …

β‐Adrenergic‐inhibiting drugs are widely prescribed for the treatment of hypertension.
These drugs have previously been found to influence a variety of psychologic and …