[HTML][HTML] Hypertension as a surrogate marker for the activity of anti-VEGF agents
O Mir, S Ropert, J Alexandre… - Annals of …, 2009 - annalsofoncology.org
found that the occurrence of hypertension [grade‡ 3 according to the National Cancer
Institute—Common Toxicity Criteria (NCI-CTC)[13]] was associated with a higher response …
Institute—Common Toxicity Criteria (NCI-CTC)[13]] was associated with a higher response …
[HTML][HTML] Blood pressure as a potential biomarker of the efficacy angiogenesis inhibitor
BI Levy - Annals of oncology, 2009 - annalsofoncology.org
Arterial hypertension is a commonly reported side-effect in all clinical trials testing all
inhibitors of angiogenesis and especially inhibitors of vascular endothelial growth factor …
inhibitors of angiogenesis and especially inhibitors of vascular endothelial growth factor …
An observational study of bevacizumab‐induced hypertension as a clinical biomarker of antitumor activity
O Mir, R Coriat, L Cabanes, S Ropert… - The …, 2011 - academic.oup.com
Background. Hypertension is a common toxicity of bevacizumab, but the frequency of
assessment of blood pressure and standardized grading remain to be defined. This study …
assessment of blood pressure and standardized grading remain to be defined. This study …
[引用][C] Angiogenesis inhibitors and hypertension: an emerging issue
DA Sica - Journal of Clinical Oncology, 2006 - ascopubs.org
Any of a number of therapeutic agents or chemical substances can induce transient or more
long-lasting forms of hypertension. Drugs that cause hypertension do so by either …
long-lasting forms of hypertension. Drugs that cause hypertension do so by either …
Analysis of early hypertension (HTN) and clinical outcome with bevacizumab (BV).
H Hurwitz, PS Douglas, JP Middleton… - Journal of Clinical …, 2010 - ascopubs.org
3039 Background: HTN is associated with anti-VEGF treatment (Tx), but this association has
not been well studied. To assess the prognostic and predictive importance of BV-related …
not been well studied. To assess the prognostic and predictive importance of BV-related …
Hypertension as a predictive marker for bevacizumab in metastatic breast cancer: results from a retrospective matched-pair analysis
SP Gampenrieder, F Romeder, C MUß… - Anticancer …, 2014 - ar.iiarjournals.org
Background: Several phase-III studies have shown improvements in terms of progression-
free survival (PFS) with bevacizumab when added to chemotherapy in advanced breast …
free survival (PFS) with bevacizumab when added to chemotherapy in advanced breast …
Early hypertension (HTN) as a potential pharmacodynamic (PD) marker for survival in pancreatic cancer (PC) patients (pts) treated with bevacizumab (B) and …
G Friberg, K Kasza, EE Vokes… - Journal of Clinical …, 2005 - ascopubs.org
3020 Background: Bevacizumab is a monoclonal Ab to the vascular endothelial growth
factor (VEGF). VEGF increases vessel permeability by stimulating endothelial nitric oxide …
factor (VEGF). VEGF increases vessel permeability by stimulating endothelial nitric oxide …
Hypertension and clinical benefit of bevacizumab in the treatment of advanced renal cell carcinoma
P Bono, H Elfving, T Utriainen, P Österlund… - Annals of …, 2009 - annalsofoncology.org
Few predictive factors for efficacy of vascular endothelial growth factor pathway-targeted
therapies have been identified. We studied whether bevacizumab treatment-related …
therapies have been identified. We studied whether bevacizumab treatment-related …
Pre-existing antihypertensive treatment predicts early increase in blood pressure during bevacizumab therapy: the prospective AVALUE cohort study
A Wicki, F Hermann, V Prêtre, R Winterhalder… - Oncology research and …, 2014 - karger.com
Background: Antiangiogenic therapy is routinely used in a variety of cancer entities.
Hypertension is the most common side effect of all currently available antiangiogenic …
Hypertension is the most common side effect of all currently available antiangiogenic …
Analysis of early hypertension and clinical outcome with bevacizumab: results from seven phase III studies
HI Hurwitz, PS Douglas, JP Middleton… - The …, 2013 - academic.oup.com
Background. Hypertension is associated with antivascular endothelial growth factor
treatment, but the clinical implications of hypertension are uncertain. To assess the …
treatment, but the clinical implications of hypertension are uncertain. To assess the …