Clinical disease caused by the agent of tuberculosis, Mycobacterium tuberculosis, and by
less virulent mycobacteria, such as bacillus Calmette-Guérin (BCG) vaccines and …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tb) and a few related
mycobacteria, is a devastating disease, killing more than a million individuals per year …

Severe mycobacterial disease is mostly confined to patients who are immunocompromized
either by acquired or inherited causes. One such genetic disorder is Mendelian …

Mendelian susceptibility to mycobacterial disease (MSMD) is a rare condition characterized
by predisposition to clinical disease caused by weakly virulent mycobacteria, such as BCG …

Selective susceptibility to weakly pathogenic mycobacteria, such as bacillus Calmette-
Guérin (BCG) vaccine and environmental non-tuberculous mycobacteria (NTM), has long …

Background Inborn errors of intrinsic and innate immunity constitute the focus of a growing
research field that investigates the molecular mechanisms underlying susceptibility to …

Introduction: Mendelian susceptibility to mycobacterial diseases (MSMD), a group of at least
18 different genetic disorders, encompasses a specific class of inborn errors of immunity that …

To gain insights into a possible immune defect predisposing to disseminated mycobacteria
infection, we studied three of six surviving children with disseminated Mycobacterium avium …

The integrity of the interferon (IFN)-γ circuit is necessary to mount an effective immune
response to intra-macrophagic pathogens, especially Mycobacteria. Inherited monogenic …

Mendelian susceptibility to poorly virulent mycobacteria such as bacillus Calmette-Guerin
(BCG) and environmental nontuberculous mycobacteria is a clinically heterogeneous …