A new series of pyrrolyl phenoxy derivatives bearing alkoxy linker were synthesized and
evaluated for anti-tubercular activity (anti-TB) against Mycobacterium tuberculosis …

In efforts to develop lead anti-TB compounds, a novel series of 19 pyrrolyl benzohydrazides
were synthesized and screened to target enoyl-ACP reductase enzyme, which is one of the …

Background: Benzothiazoles possess a vast sphere of biological activities including anti-
inflammatory, antibacterial activities whereas triazoles display various pharmacological …

We report here the synthesis, antibacterial and antitubercular evaluation of 61 novel pyrrolyl
derivatives bearing pyrazoline, isoxazole and phenyl thiourea moieties. Molecular docking …

Using novel hybrid molecules for the treatment of tuberculosis is one of the latest
approaches. Keeping this concept in mind, thirty two hybrid compounds were synthesized …

Aim: Tuberculosis (TB) is the most common deadly infectious disease caused by various
strains of mycobacteria, usually Mycobacterium TB (MTB) in humans. Drugs used for TB are …

Tuberculosis still persist a major challenge to healthcare system around the world.
Increasing rates of morbidity, mortality and the reoccurrence of the resistant strains of the …

Background Time consumed and expenses in discovering and synthesizing new
hypothetical drugs with improved biological activity have been a major challenge toward the …

Novel 54 pyrrolyl acetohydrazide analogues were designed, synthesized and screened for
antitubercular activity against InhA. Enoyl-ACP reductase/InhA one of the significant …

In the current study, two sets of compounds:(E)-1-(2-(4-substitutedphenyl)-2-oxoethyl)-4-
((hydroxyimino) methyl) pyridinium derivatives (3a-3e); and (E)-3-(substitutedbenzoyl)-7 …