Background There is consensus that experimental autoimmune encephalomyelitis (EAE)
can be mediated by myelin specific T cells of Th1 as well as of Th17 phenotype, but the …

Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis
(EAE), are autoimmune demyelinating diseases of the central nervous system (CNS) …

It has recently been proposed that experimental autoimmune encephalomyelitis, once
considered the classical Th1 disease, is predominantly Th17 driven. In this study we show …

Experimental autoimmune encephalomyelitis (EAE) is a model of human multiple sclerosis
induced by autoreactive Th cells that mediate tissue inflammation and demyelination in the …

During the development of experimental autoimmune encephalomyelitis (EAE), the
proportion of pathogenic and myelin-specific cells within CNS-infiltrating cytokine-producing …

IL-17–producing CD8+ T (Tc17) cells are detectible in multiple sclerosis (MS) lesions;
however, their contribution to the disease is unknown. To identify functions of Tc17 cells, we …

Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis
(MS) that shares many features with the human disease. This review will focus on the role of …

Multiple sclerosis (MS) is the most important autoimmune disease of the central nervous
system (CNS). Its animal model experimental autoimmune encephalomyelitis (EAE) has …

It has been firmly established that IL-23 polarized TH17 cells are potent effectors in the
pathogenesis of experimental autoimmune encephalitomyelitis (EAE). However, the relative …

The clear association of Th17 cells with autoimmune pathogenicity implicates Th17
cytokines as critical mediators of chronic autoimmune diseases such as EAE. To study the …