Expression of placental regulatory genes is associated with fetal growth

MA Deyssenroth, Q Li, M Lacasaña… - Journal of perinatal …, 2017 - degruyter.com
The placenta is the principal organ regulating respiratory, nutritional, endocrine and
metabolic functions on behalf of the developing fetus. Changes in gene expression patterns …

[HTML][HTML] Mid-gestational gene expression profile in placenta and link to pregnancy complications

L Uusküla, J Männik, K Rull, A Minajeva, S Koks… - PLoS …, 2012 - journals.plos.org
Despite the importance of placenta in mediating rapid physiological changes in pregnancy,
data on temporal dynamics of placental gene expression are limited. We completed the first …

[HTML][HTML] Genetically-predicted placental gene expression is associated with birthweight and adult body mass index

EA Jasper, JN Hellwege, JA Piekos, SH Jones… - Scientific Reports, 2023 - nature.com
The placenta is critical to human growth and development and has been implicated in health
outcomes. Understanding the mechanisms through which the placenta influences perinatal …

Gene expression patterns in the developing murine placenta

C Gheorghe, S Moham… - Journal of the Society for …, 2006 - journals.sagepub.com
Objective: Successful placental development is crucial for optimal growth, maturation, and
survival of the embryo/fetus. To examine genetic aspects of placental development, use …

[HTML][HTML] Whole-transcriptome analysis delineates the human placenta gene network and its associations with fetal growth

MA Deyssenroth, S Peng, K Hao, L Lambertini… - BMC genomics, 2017 - Springer
Background The placenta is the principal organ regulating intrauterine growth and
development, performing critical functions on behalf of the developing fetus. The delineation …

Adaptability and potential for treatment of placental functions to improve embryonic development and postnatal health

JC Cross - Reproduction, Fertility and Development, 2016 - CSIRO Publishing
For an organ that is so critical for life in eutherian mammals, the placenta hardly gets the
attention that it deserves. The placenta does a series of remarkable things, including …

Comparative transcriptomic analysis of human placentae at term and preterm delivery

AG Paquette, HM Brockway, ND Price… - Biology of …, 2018 - academic.oup.com
Preterm birth affects 1 out of every 10 infants in the United States, resulting in substantial
neonatal morbidity and mortality. Currently, there are few predictive markers and few …

Sex-dependent differential transcript expression in the placenta of growth restricted infants

JL O'Callaghan, VL Clifton, P Prentis, A Ewing, Z Saif… - Placenta, 2022 - Elsevier
Introduction The pathological decrease of fetal growth during gestation can lead to
subsequent poor health outcomes for the fetus. This process is commonly controlled by the …

A comprehensive analysis of the human placenta transcriptome

J Saben, Y Zhong, S McKelvey, NK Dajani, A Andres… - Placenta, 2014 - Elsevier
As the conduit for nutrients and growth signals, the placenta is critical to establishing an
environment sufficient for fetal growth and development. To better understand the …

Differential placental gene expression in term pregnancies affected by fetal growth restriction and macrosomia

A Sabri, D Lai, A D'silva, S Seeho, J Kaur… - Fetal Diagnosis and …, 2014 - karger.com
Introduction: Extremes of fetal growth are associated with increased perinatal mortality and
morbidity and a higher prevalence of cardiovascular disease, obesity and diabetes in later …