Synthetic biomaterials combined with cells and osteogenic factors represent a promising
approach for the treatment of a number of orthopedic diseases, such as bone trauma and …

Today, porous nanocomposite scaffolds play a key role in tissue engineering approaches
and new processing methods and materials are constantly being developed to cater for the …

This study evaluated the potential of the PCL (poly-caprolactone)/HA (Hydroxyapatite)
composite materials as a scaffold for bone regeneration. For this, we fabricated scaffolds …

In this research, new bioactive nanocomposite scaffolds were successfully developed using
poly (ε-caprolactone)(PCL), cross-linked gelatin and nanoparticles of hydroxyapatite (HAp) …

This paper reports a novel method to prepare PCL/PLGA/HA (w/w= 6/4/2) bone tissue
scaffold through melt-blending and particle-leaching. The ultrastructural and …

In bone tissue engineering, scaffolds with controlled porosity are required to allow cell
ingrowth, nutrient diffusion and sufficient formation of vascular networks. The physical …

Major drawbacks of using an autograft are the possibilities of insufficient bony source and
patient's morbidity after operation. Bone tissue engineering technology, therefore, has been …

In this study, we aimed to improve the hydrophilicity, cellular activities and osteogenesis of
polycaprolactone (PCL) scaffolds by adding gelatin (Gel) and nano-hydroxyapatite (n-HA) …

The major challenge of tissue regeneration is to develop three dimensional scaffolds with
suitable properties which would mimic the natural extracellular matrix to induce the …

Nanoengineered biodegradable constructs based on synthetic and natural polymers
enriched with hydroxyapatite (HA) nanoparticles have been found to mimic the extracellular …