Nanoparticle-mediated pulmonary drug delivery: a review

M Paranjpe, CC Müller-Goymann - International journal of molecular …, 2014 - mdpi.com
Colloidal drug delivery systems have been extensively investigated as drug carriers for the
application of different drugs via different routes of administration. Systems, such as solid …

Nanomedicine in pulmonary delivery

HM Mansour, YS Rhee, X Wu - International journal of …, 2009 - Taylor & Francis
The lung is an attractive target for drug delivery due to noninvasive administration via
inhalation aerosols, avoidance of first-pass metabolism, direct delivery to the site of action …

Targeted delivery of nanoparticles for the treatment of lung diseases

S Azarmi, WH Roa, R Löbenberg - Advanced drug delivery reviews, 2008 - Elsevier
Targeted delivery of drug molecules to organs or special sites is one of the most challenging
research areas in pharmaceutical sciences. By developing colloidal delivery systems such …

Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases

S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …

Nanoparticles: characteristics, mechanisms of action, and toxicity in pulmonary drug delivery—a review

S Gill, R Löbenberg, T Ku, S Azarmi… - Journal of …, 2007 - ingentaconnect.com
The pulmonary route has recently gained momentum as a suitable avenue for drug delivery.
The large alveolar surface area of approximately 75 m2 coupled with the thin epithelial …

Patented therapeutic drug delivery strategies for targeting pulmonary diseases

AK Thakur, DK Chellappan, K Dua… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: Pulmonary route is one of the preferred routes for the administration of
therapeutically active agents for systemic as well as localized delivery. Chronic obstructive …

Physicochemical properties of nanoparticles affecting their fate and the physiological function of pulmonary surfactants

Q Liu, J Guan, R Song, X Zhang, S Mao - Acta biomaterialia, 2022 - Elsevier
Pulmonary drug delivery has drawn great attention due to its targeted local lung action,
reduced side effects, and ease of administration. However, inhaled nanoparticles (NPs) …

Nanostructures for drug delivery in respiratory diseases therapeutics: Revision of current trends and its comparative analysis

LÁ Ibarra-Sánchez, A Gámez-Méndez… - Journal of Drug Delivery …, 2022 - Elsevier
Respiratory diseases are leading causes of death and disability in developing and
developed countries. The burden of acute and chronic respiratory diseases has been rising …

Nanoparticles for drug delivery to the lungs

JC Sung, BL Pulliam, DA Edwards - Trends in biotechnology, 2007 - cell.com
The lungs are an attractive route for non-invasive drug delivery with advantages for both
systemic and local applications. Incorporating therapeutics with polymeric nanoparticles …

Inhalable particulate drug delivery systems for lung cancer therapy: Nanoparticles, microparticles, nanocomposites and nanoaggregates

HM Abdelaziz, M Gaber, MM Abd-Elwakil… - Journal of Controlled …, 2018 - Elsevier
There is progressive evolution in the use of inhalable drug delivery systems (DDSs) for lung
cancer therapy. The inhalation route offers many advantages, being non-invasive method of …