Resistance to platinum in tumor tissue is a considerable barrier against effective lung cancer
treatment. Radionuclide therapy is the primary adjuvant treatment, however, the toxic side …

Radioactive seed brachytherapy is a method for treating drug‑resistant, late‑stage non‑small
cell lung cancer (NSCLC). To elucidate the mechanism of low‑dose gambogic acid (GA) and …

Cisplatin resistance is a main clinical problem of lung cancer therapy. Gambogic acid (GA)
could prohibit the proliferation of a variety of human cancer cells. However, the effects of GA …

Objective: To investigate the pro-apoptotic effect of gambogenic acid (GNA) on human
colonic carcinoma HCT116 cells, and to explore the possible molecular mechanism …

Gambogic acid (GA), a major active component of gamboge, exhibits potent anticancer
activity in many kinds of cancer cells. However, the anticancer mechanism of GA is not …

Anticancer Effect and Apoptosis Induction of Gambogic Acid in Human Leukemia Cell Line K562
In Vitro - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

The natural product gambogic acid (GA) has been demonstrated to be a promising
chemotherapeutic drug for some cancers because of its ability to induce apoptosis and cell …

Ovarian cancer patients often have poor prognosis, therefore, it is important to search for
more effective therapeutic strategies to treat them. Gambogic acid (GA) exhibits an anti …

To explore gambogenic acid (GNA)-induced apoptosis and underlying mechanism in vivo.
A549 nude mice xenografts were used as in vivo model to study anticancer effect of GNA by …

Non‑small cell lung cancer (NSCLC) is the most common type of lung cancer and the most
common cause of mortality in patients with lung cancer. The efficacy of cisplatin‑based …