[HTML][HTML] Structure–activity relationships of the intramolecular disulphide bonds in LEAP2, an antimicrobial peptide from Acrossocheilus fasciatus
CG Yu, L Ma, DN Zhang, Y Ma, CY Wang… - BMC Veterinary …, 2024 - Springer
Background The liver-expressed antimicrobial peptide 2 (LEAP2) plays a pivotal role in the
host's immune response against pathogenic microorganisms. Numerous such antimicrobial …
host's immune response against pathogenic microorganisms. Numerous such antimicrobial …
Molecular characterization, antibacterial and immunoregulatory activities of liver-expressed antimicrobial peptide 2 (LEAP-2) in black rockfish, Sebastes schlegelii
M Zhang, X Yan, C Wang, W Liu, Y Wang, H Jing… - Fish & Shellfish …, 2024 - Elsevier
LEAP2 (liver expression antimicrobial peptide 2), is an antimicrobial peptide widely found in
vertebrates and mainly expressed in liver. LEAP2 plays a vital role in host innate immunity …
vertebrates and mainly expressed in liver. LEAP2 plays a vital role in host innate immunity …
Identification of antibacterial activity of liver-expressed antimicrobial peptide 2 (LEAP2) from primitive vertebrate lamprey
Y Wang, Z Wang, Z Gao, Y Luan, Q Li, Y Pang… - Fish & Shellfish …, 2024 - Elsevier
Liver-expressed antimicrobial peptide 2 (LEAP2) is a member of the antimicrobial peptides
family and plays a key role in the innate immune system of organisms. LEAP2 orthologs …
family and plays a key role in the innate immune system of organisms. LEAP2 orthologs …
[HTML][HTML] Gene structure and expression characteristics of liver-expressed antimicrobial peptide-2 isoforms in mud loach (Misgurnus mizolepis, Cypriniformes)
SY Lee, YK Nam - Fisheries and Aquatic Sciences, 2017 - Springer
Background Liver-expressed antimicrobial peptide-2 (LEAP-2) is an important component of
innate immune system in teleosts. In order to understand isoform-specific involvement and …
innate immune system in teleosts. In order to understand isoform-specific involvement and …
[HTML][HTML] Comparative study on antibacterial characteristics of the multiple liver expressed antimicrobial peptides (LEAPs) in teleost fish
X Liu, YZ Hu, YR Pan, J Liu, YB Jiang… - Frontiers in …, 2023 - frontiersin.org
Antimicrobial peptides are important components of the host innate immune system, forming
the first line of defense against infectious microorganisms. Among them, liver-expressed …
the first line of defense against infectious microorganisms. Among them, liver-expressed …
Molecular characterization and functional analysis of two distinct liver-expressed antimicrobial peptide 2 (LEAP-2) genes in large yellow croaker (Larimichthys crocea)
HX Li, XJ Lu, CH Li, J Chen - Fish & shellfish immunology, 2014 - Elsevier
Liver-expressed antimicrobial peptide 2 (LEAP-2) plays a vital role in the host innate
immune system. In the present study, two LEAP-2 genes (LcLEAP-2A and LcLEAP-2C) from …
immune system. In the present study, two LEAP-2 genes (LcLEAP-2A and LcLEAP-2C) from …
Characterization, evolution and functional analysis of the liver-expressed antimicrobial peptide 2 (LEAP-2) gene in miiuy croaker
T Liu, Y Gao, R Wang, T Xu - Fish & Shellfish Immunology, 2014 - Elsevier
As an evolutionarily older defense strategy, the innate immune is the dominant immune
system and provides a first line of antimicrobial host defense in teleost. Liver-expressed …
system and provides a first line of antimicrobial host defense in teleost. Liver-expressed …
Identification of antibacterial activity of LEAP2 from Antarctic icefish Chionodraco hamatus
Y Fei, Q Wang, J Lu, L Ouyang, W Li… - Journal of Fish …, 2023 - Wiley Online Library
Liver‐expressed antimicrobial peptide 2 (LEAP2) is a small peptide, which is consisted of
signal peptide, pro‐peptide and the bioactive mature peptide. Mature LEAP2 is an …
signal peptide, pro‐peptide and the bioactive mature peptide. Mature LEAP2 is an …
The protection effect of LEAP-2 on the mudskipper (Boleophthalmus pectinirostris) against Edwardsiella tarda infection is associated with its immunomodulatory …
Liver-expressed antimicrobial peptide 2 (LEAP-2) is a cationic peptide that plays an
important role in the host's innate immune system. However, the mechanism by which LEAP …
important role in the host's innate immune system. However, the mechanism by which LEAP …
Evolution, expression, and characterisation of liver-expressed antimicrobial peptide genes in ancient chondrostean sturgeons
S Zhang, Q Xu, H Du, Z Qi, Y Li, J Huang, J Di… - Fish & shellfish …, 2018 - Elsevier
Liver-expressed antimicrobial peptide 2 (leap-2) is an evolutionarily ancient molecule that
acts as the key component in vertebrate innate immunity against invading pathogens. Leap …
acts as the key component in vertebrate innate immunity against invading pathogens. Leap …