Introduction: Inhaled corticosteroids (ICS) alone or in combination with an inhaled long-
acting beta2-agonist (LABA) are the preferred long-term treatment for adults and …

Long acting β2-adrenoceptor agonists as exemplified by salmeterol and formoterol, exhibit
reassertion behaviour in isolated airway preparations. This phenomenon is the inhibition of …

This article presents information about various new drugs for the treatment of asthma. There
are three major approaches to the development of new anti-asthma treatments …

The synthesis and evaluation of a novel series of 1, 7-cyclized indole-based human
adrenergic receptor (β3-AR) agonists are reported. The synthesis of a variety of 1, 7-cyclized …

The design and profile of a series of saligenin containing long acting β2-adrenoreceptor
agonists is described. Evaluation of these analogues using a guinea-pig tissue model …

In an unusual paradox, asthmatics who are chronically treated with bronchodilating β-
agonists sometimes experience a worsening of their condition. A new study describes one …

Abstract β 2-Agonists that bind to plasmalemmal β 2-adrenoceptors causing cAMP
accumulation are widely used as bronchodilators in chronic respiratory diseases. Here, we …

Background: Twice− daily long− acting ß2− agonists (LABAs), such as formoterol and
salmeterol, are well established therapies in respiratory diseases like asthma and COPD. BI …

The aim of this study was to systematically compare the interaction of the long-acting beta2-
adrenoceptor agonists formoterol and salmeterol with short-acting beta2-adrenoceptor …

Agonist binding to the β 2-adrenoceptors and its mapping were studied using the newly
developed radioligand [3 H] formoterol. The results of [3 H] formoterol saturation binding and …