[HTML][HTML] Long noncoding RNA TUG1 is a diagnostic factor in lung adenocarcinoma and suppresses apoptosis via epigenetic silencing of BAX

H Liu, G Zhou, X Fu, H Cui, G Pu, Y Xiao, W Sun… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Lung cancer is one of the leading causes of cancer-related mortality, and responds badly to
existing treatment. Thus, it is of urgent need to identify novel diagnostic markers and …

[HTML][HTML] Long noncoding RNA TUG1 is downregulated in non-small cell lung cancer and can regulate CELF1 on binding to PRC2

PC Lin, HD Huang, CC Chang, YS Chang, JC Yen… - BMC cancer, 2016 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) play crucial roles in tumorigenesis,
and lncRNA taurine-upregulated gene 1 (TUG1) has been proven to be associated with …

[HTML][HTML] Long non-coding RNA TUG1 as a potential prognostic biomarker in human cancers: a meta-analysis

PJ Ma, QK Guan, L Meng, N Qin, J Zhao, BZ Jin - Oncotarget, 2017 - ncbi.nlm.nih.gov
LncRNA taurine upregulated gene 1 (TUG1) is reportedly dysregulated in various cancers.
We performed this meta-analysis to clarify the usefulness of TUG1 as a prognostic marker in …

[HTML][HTML] The prognostic potential and carcinogenesis of long non-coding RNA TUG1 in human cholangiocarcinoma

Y Xu, K Leng, Z Li, F Zhang, X Zhong, P Kang, X Jiang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Cholangiocarcinoma (CCA) is a fatal disease with increasing worldwide incidence and is
characterized by poor prognosis due to its poor response to conventional chemotherapy or …

[HTML][HTML] Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2

Y Niu, F Ma, W Huang, S Fang, M Li, T Wei, L Guo - Molecular cancer, 2017 - Springer
Background Taurine upregulated gene1 (TUG1) as a 7.1-kb lncRNA, has been shown to
play an oncogenic role in various cancers. However, the biological functions of lncRNA …

[HTML][HTML] Long non-coding RNA TUG1 promotes cell progression in hepatocellular carcinoma via regulating miR-216b-5p/DLX2 axis

Q Dai, J Deng, J Zhou, Z Wang, X Yuan, S Pan… - Cancer cell …, 2020 - Springer
Background Accumulating evidence indicates that the long noncoding RNA taurine
upregulated gene 1 (TUG1) plays a critical role in cancer progression and metastasis …

[HTML][HTML] P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 …

EB Zhang, DD Yin, M Sun, R Kong, XH Liu… - Cell death & …, 2014 - nature.com
Recently, a novel class of transcripts, long non-coding RNAs (lncRNAs), is being identified
at a rapid pace. These RNAs have critical roles in diverse biological processes, including …

TUG 1: a pivotal oncogenic long non‐coding RNA of human cancers

Z Li, J Shen, MTV Chan, WKK Wu - Cell proliferation, 2016 - Wiley Online Library
Long non‐coding RNA s (lnc RNA s) are a group greater than 200 nucleotides in length. An
increasing number of studies has shown that lnc RNA s play important roles in diverse …

[HTML][HTML] Long non-coding RNA TUG1 enhances chemosensitivity in non-small cell lung cancer by impairing microRNA-221-dependent PTEN inhibition

S Guo, L Zhang, Y Zhang, Z Wu, D He, X Li… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Long non-coding RNA taurine up-regulated gene 1 (TUG1) emerges as new players in gene
regulation in several cancers; however, its mechanism of action in non-small cell lung …

[HTML][HTML] The long non-coding RNA TUG1 indicates a poor prognosis for colorectal cancer and promotes metastasis by affecting epithelial-mesenchymal transition

J Sun, C Ding, Z Yang, T Liu, X Zhang, C Zhao… - Journal of translational …, 2016 - Springer
Background Long intergenic non-coding RNAs (lncRNAs) are a class of non-coding RNAs
that are involved in gene expression regulation. Taurine up-regulated gene 1 (TUG1) is a …