Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2

MD Huang, WM Chen, FZ Qi, M Sun, TP Xu, P Ma… - Molecular cancer, 2015 - Springer
Background Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related
death worldwide, and the biology of this cancer remains poorly understood. Recent …

Increased expression of long noncoding RNA TUG1 predicts a poor prognosis of gastric cancer and regulates cell proliferation by epigenetically silencing of p57

E Zhang, X He, D Yin, L Han, M Qiu, T Xu, R Xia… - Cell death & …, 2016 - nature.com
Recent evidence highlights long noncoding RNAs (lncRNAs) as crucial regulators of cancer
biology that contribute to tumorigenesis. LncRNA TUG1 was initially detected in a genomic …

[HTML][HTML] Prognostic value of long non-coding RNA TUG1 in various tumors

N Li, K Shi, X Kang, W Li - Oncotarget, 2017 - ncbi.nlm.nih.gov
Taurine up-regulated gene 1 (TUG1) is a long non-coding RNA (lncRNA), has been
reported that be dysregulated in various tumors, involved in proliferation and apoptosis in a …

[HTML][HTML] Overexpression of long non-coding RNA TUG1 promotes colon cancer progression

H Zhai, M Sui, X Yu, Z Qu, J Hu, H Sun… - … medical journal of …, 2016 - ncbi.nlm.nih.gov
Background Colon cancer is one of the most prevalent and deadly cancers worldwide. It is
still necessary to further define the mechanisms and explore therapeutic targets of colon …

LncRNA TUG1 contributes to ESCC progression via regulating miR‐148a‐3p/MCL‐1/Wnt/β‐catenin axis in vitro

Y Tang, P Yang, Y Zhu, Y Su - Thoracic cancer, 2020 - Wiley Online Library
Background Esophageal squamous cell carcinoma (ESCC) is one of the most lethal
malignancies. Latest studies report that long noncoding RNAs (LncRNAs) play an essential …

Downregulation of the long non-coding RNA TUG1 is associated with cell proliferation, migration, and invasion in breast cancer

S Fan, Z Yang, Z Ke, K Huang, N Liu, X Fang… - Biomedicine & …, 2017 - Elsevier
Recent studies have identified many long non-coding RNAs (lncRNAs) with critical roles in
various biological processes including tumorigenesis. Taurine-upregulated gene 1 (TUG1) …

High TUG1 expression is associated with chemotherapy resistance and poor prognosis in esophageal squamous cell carcinoma

L Jiang, W Wang, G Li, C Sun, Z Ren, H Sheng… - Cancer chemotherapy …, 2016 - Springer
Abstract Purpose Long noncoding RNAs (lncRNAs) play critical roles in diverse biological
processes such as tumorigenesis and metastasis. Taurine upregulated gene 1 (TUG1) is a …

Long non-coding RNA TUG1 promotes cell proliferation and metastasis by negatively regulating miR-300 in gallbladder carcinoma

F Ma, S Wang, Q Cai, L Jin, D Zhou, J Ding… - Biomedicine & …, 2017 - Elsevier
Background As we all know, long non-coding RNAs (lncRNAs) have been reported to play
vital roles in various human cancers. In this study, we aimed to explore the role of lncRNA …

Downregulation of long noncoding RNA TUG1 inhibits proliferation and induces apoptosis through the TUG1/miR-142/ZEB2 axis in bladder cancer cells

Q Liu, H Liu, H Cheng, Y Li, X Li, C Zhu - OncoTargets and therapy, 2017 - Taylor & Francis
Background Bladder cancer is a common serious disease around the world. Long
noncoding RNAs (lncRNAs) have been demonstrated to participate in the development and …

Molecular mechanisms of TUG1 in the proliferation, apoptosis, migration and invasion of cancer cells

H Zhou, L Sun, F Wan - Oncology letters, 2019 - spandidos-publications.com
Long non‑coding RNAs (lncRNAs) are RNA sequences> 200 nucleotides in length that have
no protein‑coding capacity. lncRNAs serve key roles in multiple biological processes, such …