Aflatoxin-induced upregulation of protein arginine methyltransferase 5 is mediated by protein kinase C and extracellular signal-regulated kinase
Aflatoxins are fungal metabolites classified into four major groups such as B 1, B 2, G 1, and
G 2. These natural aflatoxins are designated as group I carcinogen by the International …
G 2. These natural aflatoxins are designated as group I carcinogen by the International …
Aflatoxin B1 induced upregulation of protein arginine methyltransferase 5 in human cell lines
The exposure of naturally occurring mycotoxins affects human health and play a vital role in
cancer initiation and progression. Aflatoxin B 1 is a difuranocoumarin mycotoxin, classified …
cancer initiation and progression. Aflatoxin B 1 is a difuranocoumarin mycotoxin, classified …
Protein arginine methyltransferase 5 is essential for growth of lung cancer cells
Z Gu, S Gao, F Zhang, Z Wang, W Ma… - Biochemical …, 2012 - portlandpress.com
PRMT5 (protein arginine methyltransferase 5) is an enzyme that catalyses transfer of methyl
groups from S-adenosyl methionine to the arginine residues of histones or non-histone …
groups from S-adenosyl methionine to the arginine residues of histones or non-histone …
Curcumin ameliorates PRMT5-MEP50 arginine methyltransferase expression by decreasing the Sp1 and NF-YA transcription factors in the A549 and MCF-7 cells
B Chatterjee, K Ghosh, L Suresh… - Molecular and Cellular …, 2019 - Springer
The protein arginine methyltransferase 5 (PRMT5) and its catalytic partner methylosome
protein MEP50 (WDR77) catalyse the mono-and symmetric di-methylation of selective …
protein MEP50 (WDR77) catalyse the mono-and symmetric di-methylation of selective …
[HTML][HTML] Role of protein arginine methyltransferase 5 in human cancers
W Xiao, X Chen, L Liu, Y Shu, M Zhang… - Biomedicine & …, 2019 - Elsevier
Protein arginine methyltransferases (PRMTs) play important roles in protein methylation.
PRMT5 is the major type II arginine methyltransferase that catalyzes the transfer of two …
PRMT5 is the major type II arginine methyltransferase that catalyzes the transfer of two …
[HTML][HTML] Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3
B Zhang, S Dong, R Zhu, C Hu, J Hou, Y Li, Q Zhao… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Protein arginine methyltransferases (PRMTs) plays critical roles in cancer. PRMT5 has been
implicated in several types of tumors. However, the role of PRMT5 in cancer development …
implicated in several types of tumors. However, the role of PRMT5 in cancer development …
[HTML][HTML] Arginine methyltransferase inhibitor‑1 inhibits sarcoma viability in vitro and in vivo
B Zhang, X Chen, S Ge, C Peng… - Oncology …, 2018 - spandidos-publications.com
Protein arginine methyltransferases (PRMTs) are a class of epigenetic modified enzymes
that are overexpressed in a various types of cancer and serve pivotal functions in malignant …
that are overexpressed in a various types of cancer and serve pivotal functions in malignant …
Knockdown of PRMT1 suppresses the malignant biological behavior of osteosarcoma cells and increases cisplatin sensitivity via c‐Myc‐mediated BCAT1 …
Z Li, D Meng, Y Liu, F Bi, K Tian, J Xu… - … of Biochemical and …, 2024 - Wiley Online Library
Increasing evidence indicated that protein arginine methyltransferase‐1 (PRMT1) is an
oncogene in multiple malignant tumors, including osteosarcoma (OS). The aim of this study …
oncogene in multiple malignant tumors, including osteosarcoma (OS). The aim of this study …
Arginine methyltransferase inhibitor 1 inhibits gastric cancer by downregulating eIF4E and targeting PRMT5
B Zhang, S Zhang, L Zhu, X Chen, Y Zhao… - Toxicology and applied …, 2017 - Elsevier
Arginine methylation is carried out by protein arginine methyltransferase (PRMTs) family.
Arginine methyltransferase inhibitor 1 (AMI-1) is mainly used to inhibit type I PRMT activity in …
Arginine methyltransferase inhibitor 1 (AMI-1) is mainly used to inhibit type I PRMT activity in …
[HTML][HTML] Protein arginine methyltransferase 5 promotes lung cancer metastasis via the epigenetic regulation of miR-99 family/FGFR3 signaling
P Jing, N Zhao, M Ye, Y Zhang, Z Zhang, J Sun… - Cancer letters, 2018 - Elsevier
Abstract Protein arginine methyltransferase 5 (PRMT5) functions as a tumor initiator to
regulate several cancer progressions, such as proliferation and apoptosis, by catalyzing the …
regulate several cancer progressions, such as proliferation and apoptosis, by catalyzing the …