The asialoglycoprotein receptor (ASGPR) is the first lectin discovered in mammals. Despite
its significant biological role in binding and internalization of desialyated glycoproteins, at …

Asialoglycoprotein receptor (ASGP-R) has been actively investigated for targeted delivery of
therapeutic agents into hepatocytes because this receptor is selectively and highly …

Since the asialoglycoprotein receptor (also known as the “Ashwell–Morell receptor” or
ASGPR) was discovered as the first cellular mammalian lectin, numerous drug delivery …

The asialoglycoprotein receptor is a calcium-dependent, carbohydrate-specific, type C
lectin, which is majorly present in the plasma membrane of liver cells (hepatocytes). The …

Hepatocyte resident afflictions continue to affect the human population unabated. The
asialoglycoprotein receptor (ASGPR) is primarily expressed on hepatocytes and minimally …

The ASGP-R, exclusively located on the cell surfaces of hepatocytes, is well known for
removing desialylated glycoproteins with terminal galactose or N-acetylgalactosamine …

Mammalian liver expresses endocytic cell surface receptors that specifically bind natural or
synthetic molecules containing terminal galactosyl or N-acetylgalactosaminyl sugars. One of …

The mammalian asialoglycoprotein receptor (ASGPR) is located on the sinusoidal
membrane of hepatocytes where it binds and endocytoses galactose-terminated …

The human asialoglycoprotein receptor (ASGPR) represents a major component of the
hepatocellular membrane. To study its native composition, approximately 30% of receptor …

280 AL Schwartz, HJ Geuze and GJAM Strous hepatocyte serves as an excellent model of a
complex polarized epithelium which actively takes up and targets exogenous ligands via …