Procedures for surgically accessing and removing lesions of the sella turcica have
interested pituitary surgeons since the late 1800s. Pierre Marie's landmark paper in 1886 [1] …

Like many other technologic or scientific advances, the events that led to the development
and widespread acceptance of the transsphenoidal approach to lesions of the sellar region …

Pituitary surgery is a continuously evolving specialty of neurosurgery that requires precise
anatomical knowledge, technical skills, and an integrated appreciation of pituitary …

Despite ongoing advances in the pharmacological, radiotherapeutic and endocrine
management of pituitary tumours, surgery remains the therapy of choice for the large …

This paper reviews the progress made over the first century of pituitary surgery. The goals of
surgery for pituitary tumors are to eliminate tumor mass effect and perform as complete a …

The surgical treatment of pituitary tumours underwent considerable evolution during the past
centennial. Since Schloffer's first description, excellent surgeons refined the surgical …

Most pituitary tumors, even large lesions, are treated quite effectively via the transsphenoidal
approach to the sella. At times, however, pituitary tumors grow outside the bounds of the …

✓ Initial attempts at transcranial approaches to the pituitary gland in the late 1800s and early
1900s resulted in a mortality rate that was generally considered prohibitive. Schloffer …

Abstract THE TRANSSPHENOIDAL APPROACH for sellar tumors has evolved significantly
since it was described initially during the first decade of the 20th century. The approach …

Although the transsphenoidal approach is preferred for a majority of pituitary tumor
resections, modern pituitary surgery is built on a long history of varied approaches to the …