Expression of CD 56 is an unfavorable prognostic factor for acute promyelocytic leukemia with higher initial white blood cell counts

T Ono, A Takeshita, Y Kishimoto, H Kiyoi… - Cancer …, 2014 - Wiley Online Library
Expression of CD 56 has recently been introduced as one of the adverse prognostic factors
in acute promyelocytic leukemia (APL). However, the clinical significance of CD 56 antigen …

CD34 expression is associated with poor clinical outcome in patients with acute promyelocytic leukemia

JJ Lee, D Cho, IJ Chung, SH Cho… - American journal of …, 2003 - Wiley Online Library
This study investigated the clinical characteristics and prognostic relevance of CD34
expression in 47 patients with acute promyelocytic leukemia (APL), showing t (15; 17) or …

Clinical and biological significance of CD56 antigen expression in acute promyelocytic leukemia

S Ito, Y Ishida, T Oyake, M Satoh, Y Aoki… - Leukemia & …, 2004 - Taylor & Francis
The biological significance of CD56 antigen expression in patients with acute promyelocytic
leukemia (APL) has been under investigation. We investigated the clinical and biologic …

Negative prognostic value of CD34 antigen also if expressed on a small population of acute promyelocitic leukemia cells

M Breccia, MS De Propris, C Stefanizzi, S Raponi… - Annals of …, 2014 - Springer
Potential clinical significance of CD34 expression in acute promyelocitic leukemia (APL) has
not been deeply investigated. We hereby analyzed the clinico-biological features and …

CD56 expression in acute promyelocytic leukemia: a possible indicator of poor treatment outcome?

CK Murray, E Estey, E Paietta, RS Howard… - Journal of Clinical …, 1999 - ascopubs.org
PURPOSE: Blast expression of CD56 is frequent in patients with t (8; 21)(q22; q22) acute
myeloid leukemia and is associated with an inferior outcome. The expression of CD56 has …

Clinical significance of CD56 expression in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based regimens

P Montesinos, C Rayón, E Vellenga… - Blood, The Journal …, 2011 - ashpublications.org
The expression of CD56 antigen in acute promyelocytic leukemia (APL) blasts has been
associated with short remission duration and extramedullary relapse. We investigated the …

CD34‐positive acute promyelocytic leukemia is associated with leukocytosis, microgranular/hypogranular morphology, expression of CD2 and bcr3 isoform

R Foley, P Soamboonsrup, RF Carter… - American journal of …, 2001 - Wiley Online Library
Acute promyelocytic leukemia (APL) has a favorable prognosis. Current therapy includes
chemotherapy used in combination with all‐trans‐retinoic acid (ATRA). Although the …

The biological characteristics of adult CD34+ acute promyelocytic leukemia

EI Ahmad, HK Akl, ME Hashem, TAM Elgohary - Medical Oncology, 2012 - Springer
We aimed to explore the expression of CD34 and its impact on the disease outcome in
patients with APL. The study comprised 40 de novo APL patients. Diagnostic tools included …

Aberrant phenotypic expression of CD15 and CD56 identifies poor prognostic acute promyelocytic leukemia patients

M Breccia, MS De Propris, C Minotti, C Stefanizzi… - Leukemia Research, 2014 - Elsevier
Limited information is available on the relationship between expression of some additional
aberrant phenotypic features and outcome of acute promyelocytic leukemia (APL) patients …

CD56 expression is an indicator of poor clinical outcome in patients with acute promyelocytic leukemia treated with simultaneous all-trans-retinoic acid and …

F Ferrara, F Morabito, B Martino, G Specchia… - Journal of Clinical …, 2000 - ascopubs.org
PURPOSE: Preliminary reports suggest that leukemic cell expression of CD56, a neural cell
adhesion molecule, is associated with adverse clinical outcome in either acute myeloid …