The term ''oxidative stress” refers to a cell's state characterized by excessive production of
reactive oxygen species (ROS) and oxidative stress is one of the most important regulatory …

Stem cells are defined by their ability to self‐renew and their multi‐potent differentiation
capacity. As such, stem cells maintain tissue homeostasis throughout the life of a …

Redox signaling plays important roles in the regulation of cell death and survival in
response to cancer therapy. Autophagy and apoptosis are discrete cellular processes …

Cancer is a dysregulated cellular level pathological condition that results in tumor formation
followed by metastasis. In the heterogeneous tumor architecture, cancer stem cells (CSCs) …

Reactive oxygen species (ROS) constantly generated inside the body are required to drive
regulatory pathways and are also a cause for several pathological conditions including …

Reactive oxygen species (ROS) play an important role in determining the fate of normal
stem cells. Low levels of ROS are required for stem cells to maintain quiescence and self …

Cancer cell can reprogram their energy production by switching mitochondrial oxidative
phosphorylation to glycolysis. However, mitochondria play multiple roles in cancer cells …

Cellular ROS production participates in various cellular functions but its accumulation
decides the cell fate. Malignant cells have higher levels of ROS and active antioxidant …

Significance: Reactive oxygen species (ROS), byproducts of aerobic metabolism, are
increased in many types of cancer cells. Increased endogenous ROS lead to adaptive …

Reactive oxygen species (ROS) have been identified as signaling molecules in various
pathways regulating both cell survival and cell death. Autophagy, a self-digestion process …