Genetic risk score predicts risk for overweight and obesity in Finnish preadolescents

H Viljakainen, E Dahlström, R Figueiredo… - Clinical …, 2019 - Wiley Online Library
Common genetic variants predispose to obesity with varying contribution by age. We
incorporated known genetic variants into genetic risk scores (GRSs) and investigated their …

Sex differences in heritability of BMI: a comparative study of results from twin studies in eight countries

K Schousboe, G Willemsen, KO Kyvik… - Twin Research and …, 2003 - cambridge.org
Body mass index (BMI), a simple anthropometric measure, is the most frequently used
measure of adiposity and has been instrumental in documenting the worldwide increase in …

Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index

W Wen, W Zheng, Y Okada, F Takeuchi… - Human molecular …, 2014 - academic.oup.com
Recent genetic association studies have identified 55 genetic loci associated with obesity or
body mass index (BMI). The vast majority, 51 loci, however, were identified in European …

Differential effect of polymorphisms on body mass index across the life course of Japanese: the Japan multi-institutional collaborative cohort study

M Iwase, K Matsuo, M Nakatochi, I Oze, H Ito… - Journal of …, 2021 - jstage.jst.go.jp
Background: Obesity is a reported risk factor for various health problems. Genome-wide
association studies (GWASs) have identified numerous independent loci associated with …

Gene‐by‐age effects on BMI from birth to adulthood: The Fels longitudinal study

AC Choh, M Lee, JW Kent, VP Diego, W Johnson… - …, 2014 - Wiley Online Library
Objectives Genome wide association studies have shown 32 loci to influence BMI in
European‐American adults but replication in other studies is inconsistent and may be …

The impact of genetic variants on BMI increase during childhood versus adulthood

MG Hohenadel, LJ Baier, P Piaggi, YL Muller… - International Journal of …, 2016 - nature.com
Background: Genetic variants that predispose individuals to obesity may have differing
influences during childhood versus adulthood, and additive effects of such variants are likely …

Gene-diet interaction effects on BMI levels in the Singapore Chinese population

X Chang, R Dorajoo, Y Sun, Y Han, L Wang, CC Khor… - Nutrition journal, 2018 - Springer
Background Recent genome-wide association studies (GWAS) have identified 97 body-
mass index (BMI) associated loci. We aimed to evaluate if dietary intake modifies BMI …

Associations of genetic risk score with obesity and related traits and the modifying effect of physical activity in a Chinese Han population

J Zhu, RJF Loos, L Lu, G Zong, W Gan, X Ye, L Sun… - PloS one, 2014 - journals.plos.org
Background/Objectives Recent large-scale genome-wide association studies have identified
multiple loci robustly associated with BMI, predominantly in European ancestry (EA) …

[PDF][PDF] Genome-wide association studies of common obesity: now and future

XI Bo, MI Jie - Biomedical and Environmental Sciences, 2013 - besjournal.com
Obesity has become a major public health concern worldwide [1]. Obesity is a complex
disease influenced by both genetic and environmental factors. Epidemiological studies have …

Risk variants of obesity associated genes demonstrate BMI raising effect in a large cohort

M Saqlain, M Khalid, M Fiaz, S Saeed… - Plos one, 2022 - journals.plos.org
Obesity is highly polygenic disease where several genetic variants have been reportedly
associated with obesity in different ethnicities of the world. In the current study, we identified …