Aims/hypothesis Obesity is a major risk factor for type 2 diabetes. Recent genome-wide
association (GWA) studies have identified multiple loci robustly associated with BMI and risk …

Objective: The objective of the study was to identify predictors of BMI in German adults by
considering the BMI distribution and to determine whether the association between BMI and …

Genome-wide association studies (GWAS) have revolutionised the discovery of genes for
common traits and diseases, including obesity-related traits. In less then four years time, 52 …

Before the advent of genome-wide association studies (GWASs), hundreds of candidate
genes for obesity-susceptibility had been identified through a variety of approaches. We …

Genetic loci for body mass index (BMI) in adolescence and young adulthood, a period of
high risk for weight gain, are understudied, yet may yield important insight into the etiology of …

The complex interplay between genes and environment affecting body mass gain over
lifecycle periods of risk is not well understood. We use longitudinal sibling cohort data to …

Objective: To investigate the interplay between genetic factors influencing baseline level
and changes in BMI in adulthood. Methods and Procedures: A longitudinal twin study of the …

We hypothesized that monogenic syndromic obesity genes are also involved in the
polygenic variation of BMI. Single-marker, tag single nucleotide polymorphism (tagSNP) and …

Objectives: The life-course development of body mass index (BMI) may be driven by
interactions between genes and obesity-inducing social environments. We examined …

Background Interplay between lifestyle risk scores (LRSs) and genetic risk scores (GRSs) on
obesity and related chronic diseases are underinvestigated and necessary for …