Endocrine disrupting activities and immunomodulatory effects in lymphoblastoid cell lines of diclofenac, 4-hydroxydiclofenac and paracetamol

I Klopčič, T Markovič, I Mlinarič-Raščan, MS Dolenc - Toxicology letters, 2018 - Elsevier
A critical literature review reveals that knowledge of side effects of pharmaceuticals
diclofenac and paracetamol is extremely important because of their widespread use and …

Effects of 4-nonylphenol and/or diisononylphthalate on THP-1 cells: impact of endocrine disruptors on human immune system parameters

A Bennasroune, L Rojas, L Foucaud… - International journal …, 2012 - journals.sagepub.com
The aim of the present work is to investigate the link between two endocrine disruptor
compounds (EDCs), which are chemicals that interfere with the hormone system in human …

Investigation of the immunogenicity of diclofenac and diclofenac metabolites

DJ Naisbitt, LS Sanderson, X Meng, AV Stachulski… - Toxicology letters, 2007 - Elsevier
Oral administration of the non-steroidal anti-inflammatory drug diclofenac (DCF) is
associated with a high incidence of adverse drug reactions, some of which are thought to be …

Immunomodulatory and hematological effects induced by diclofenac, ibuprofen or paracetamol toxicity in Swiss albino mice

S Gomaa - European Journal of Biological Research, 2017 - journals.tmkarpinski.com
Anti-inflammatory drugs (both COX-2 inhibitors and nonselective non-steroidal anti-
inflammatory drugs= NSAIDs), paracetamol and opioid agents are associated with …

[HTML][HTML] Immunomodulatory effects of synthetic endocrine disrupting chemicals on the development and functions of human immune cells

K Nowak, E Jabłońska, W Ratajczak-Wrona - Environment international, 2019 - Elsevier
Endocrine disrupting chemicals (EDCs) are added to food, cosmetics, plastic packages, and
children's toys and have thus become an integral part of the human environment. In the last …

[HTML][HTML] Impact of endocrine disruptors on peripheral blood mononuclear cells in vitro: role of gender

A Maddalon, L Cari, M Iulini, MN Alhosseini… - Archives of …, 2023 - Springer
Humans can be exposed to endocrine disruptors (EDs) in numerous ways. EDs can interfere
with endogenous hormones at different levels, resulting in numerous adverse human health …

Steroid hormones, endocrine disrupting compounds and immunotoxicology

E Corsini, F Ruffo, M Racchi - Current Opinion in Toxicology, 2018 - Elsevier
Endogenous steroid hormones and endocrine disrupting compounds (EDC) can
significantly affect the immune responses. While it is well established that hormonal …

[PDF][PDF] Diclofenac induced toxic manifestations on adjuvant induced arthritic rats pheripheral and reproductive organ of male wistar rats rattus norvegicus

S Subramanian - J Toxicol Environ Health Sci, 2009 - academicjournals.org
Non-Steroidal Anti-inflammatory Drugs (NSAIDs) are the most frequently prescribed
therapeutic agents, used for the treatment of rheumatic diseases, because they have …

Effect of endocrine disrupters on immune responses in vitro

U Yamashita, T Sugiura, E Kuroda - Journal of UOEH, 2002 - jstage.jst.go.jp
It has been reported that endocrine disrupters (EDs) have several biological activities,
especially on endocrine systems. We studied the effect of EDs such as diethyl stilbesterol …

[HTML][HTML] Effects of endocrine disruptor compounds, alone or in combination, on human macrophage-like THP-1 cell response

N Couleau, J Falla, A Beillerot, E Battaglia… - PLoS …, 2015 - journals.plos.org
The aim of the present study was to evaluate the immunological effects on human
macrophages of four endocrine disruptor compounds (EDCs) using the differentiated human …