In this study, synthetic vaccine nanoparticles (SVNPs) that efficiently targeted lymph nodes,
where immune responses against foreign antigens are primed, were developed to enhance …

Targeting dendritic cells (DCs), either ex vivo (Ex. Sipuleucel-T) or in vivo, for stimulating
cellular immunity has been a leading approach for cancer vaccines. We have rationally …

Among approaches of current cancer immunotherapy, a dendritic cell (DC)-targeted vaccine
based on nanotechnology could be a promising way to efficiently induce potent immune …

The well‐designed activation of dendritic cells (DCs) by enhancing the delivery of antigens
and immunostimulatory adjuvants into DCs is a key strategy for efficient cancer …

Nanoparticle‐adjuvanted cancer vaccines are attracting increasing attention because they
can induce an effective anticancer immune response. Single‐antigen vaccines are …

Using nanotechnology for cancer vaccine design holds great promise because of the
intrinsic feature of nanoparticles in being captured by antigen-presenting cells (APCs) …

Metal-organic frameworks (MOFs) have high surface area, tunable pore size, and high
loading capacity, making them promising for drug delivery. However, their synthesis requires …

Although cancer vaccine-based immunotherapy holds great potential for cancer treatment,
tumor-induced dendritic cell (DC) dysfunction remains to be the major obstacle for …

Vaccines provide a powerful tool to modulate the immune system for human disease
prevention and treatment. Classical vaccines mainly initiate immune responses in the lymph …

Identification of tumor-specific mutations, called neoantigens, offers new exciting
opportunities for personalized cancer immunotherapy. However, it remains challenging to …