Eculizumab use in catastrophic antiphospholipid syndrome (CAPS): Descriptive analysis from the “CAPS Registry”

B López-Benjume, I Rodríguez-Pintó, MC Amigo… - Autoimmunity …, 2022 - Elsevier
Objectives To describe the real-world experience of eculizumab use in patients with
catastrophic antiphospholipid syndrome (CAPS) according to the information provided by …

Eculizumab in refractory catastrophic antiphospholipid syndrome: a case report and systematic review of the literature

MG Tinti, V Carnevale, M Inglese, F Molinaro… - Clinical and …, 2019 - Springer
Catastrophic antiphospholipid syndrome (CAPS) is a rare disorder, characterized by the
development of multiple vascular thrombosis over a short period of time, in patients with …

Patients with refractory catastrophic antiphospholipid syndrome respond inconsistently to eculizumab

CM Yelnik, S Miranda, A Mékinian… - Blood, The Journal …, 2020 - ashpublications.org
Complement was identified as a critical pathway for the development of obstetrical
manifestations of the antiphospholipid syndrome (APS), and its life-threatening variant …

36‐year‐old female with catastrophic antiphospholipid syndrome treated with eculizumab: a case report and review of literature

M Strakhan, M Hurtado-Sbordoni… - Case reports in …, 2014 - Wiley Online Library
Catastrophic antiphospholipid syndrome (CAPS) is a rare but potentially life‐threatening
condition characterized by diffuse vascular thrombosis, leading to multiple organ failure …

Eculizumab induces sustained remission in a patient with refractory primary catastrophic antiphospholipid syndrome

TA Zikos, J Sokolove, N Ahuja… - JCR: Journal of Clinical …, 2015 - journals.lww.com
Catastrophic antiphospholipid syndrome (CAPS) is fatal in approximately 44% of patients in
whom the diagnosis is made, thus demonstrating the inadequacy of current medical therapy …

Catastrophic antiphospholipid syndrome: an update.

G Espinosa, I Rodríguez-Pintó, R Cervera - Panminerva Medica, 2017 - europepmc.org
Catastrophic antiphospholipid syndrome (CAPS) is a rare variant that accounts for 1% of
patients with APS. Despite its low frequency, the mortality-related is very high ranging from …

Brief report: induction of sustained remission in recurrent catastrophic antiphospholipid syndrome via inhibition of terminal complement with eculizumab

I Shapira, D Andrade, SL Allen… - Arthritis & …, 2012 - Wiley Online Library
Objective Catastrophic antiphospholipid syndrome (CAPS) is characterized by
histopathologic evidence of small vessel thrombosis, dysfunction of multiple organs …

[HTML][HTML] Efficacy of eculizumab in a patient with immunoadsorption-dependent catastrophic antiphospholipid syndrome: a case report

A Kronbichler, R Frank, M Kirschfink, A Szilagyi… - Medicine, 2014 - journals.lww.com
Efficacy of Eculizumab in a Patient With Immunoadsorption-De... : Medicine Efficacy of
Eculizumab in a Patient With Immunoadsorption-Dependent Catastrophic Antiphospholipid …

Catastrophic antiphospholipid syndrome: The current management approach

I Rodriguez-Pintó, G Espinosa, R Cervera - Best Practice & Research …, 2016 - Elsevier
The current recommendation for catastrophic antiphospholipid syndrome (CAPS)
management is the standard triple therapy with anticoagulation (AC), glucocorticoids (GCs) …

The diagnosis and clinical management of the catastrophic antiphospholipid syndrome: a comprehensive review

R Cervera, I Rodríguez-Pintó, G Espinosa - Journal of autoimmunity, 2018 - Elsevier
The catastrophic antiphospholipid syndrome (CAPS) is a life-threating variant of the
antiphospholipid syndrome characterized by the development of multiple thrombosis in a …