Objective Geriatric depression is difficult to treat and frequently accompanied by cognitive
complaints that increase risk for dementia. New treatment strategies targeting both …

Objective The objective of the study is to assess combined antidepressant and memantine
treatment in older patients presenting with depression and cognitive impairment. Methods …

Objective The present study investigated the efficacy and tolerability of escitalopram in the
prevention of relapse of major depressive disorder (MDD) in older patients who had …

Objective Management of depression in elderly patients presents a significant medical
challenge, and there is a need for further clinical trials. The authors examined the efficacy …

Objective The present study examined the efficacy and tolerability of acute escitalopram
treatment in depressed patients aged 60 years or older. Methods Patients aged≥ 60 years …

Objective Approximately half of older patients treated for major depressive disorder (MDD)
do not achieve symptomatic remission and functional recovery with first‐line …

BACKGROUND:: Comorbid depression and anxiety may result in greater symptom severity
and poorer treatment response than either condition alone. Selective serotonin reuptake …

Aim: The primary aim was to investigate the long-term safety and tolerability of escitalopram
(10 or 20 mg/day) treatment of elderly patients suffering from major depressive disorder. The …

Objective More than half of the older adults respond only partially to first‐line antidepressant
pharmacotherapy. Our objective was to test the hypothesis that a depression‐specific …

Objective To assess combined antidepressant and cognitive enhancer treatment in elderly
patients presenting with depression plus cognitive impairment. Methods Twenty‐three …