The immune correlates of protection for most of the currently used vaccines are based on
long-lived humoral immunity. Vaccines based on humoral immunity alone are unlikely to …

Background We previously observed that the nine-member family of autotransported
polymorphic membrane proteins (Pmps) of Chlamydia trachomatis is variably expressed in …

Major impediments to developing a Chlamydia vaccine lie in identifying immunologically
relevant T-cell antigens and delivery in a manner to stimulate protective immunity. Using an …

Chlamydia trachomatis (Ct) whole-proteome microarrays were utilized to identify antibody
patterns associated with infection; pelvic inflammatory disease (PID), tubal factor infertility …

We developed an RNA-Seq-based method to simultaneously capture prokaryotic and
eukaryotic expression profiles of cells infected with intracellular bacteria. As proof of …

Genital infection with Chlamydia trachomatis is an escalating global public health concern
causing considerable morbidity and socioeconomic burden worldwide. Although antibiotics …

Urgently needed species-specific ELISAs for detection of antibodies against Chlamydia (C.)
spp. have been elusive due to high cross-reactivity of chlamydial antigens. To identify …

Chlamydia trachomatis is a human pathogen of the genital tract and ocular epithelium. It is
an obligate intracellular parasite with a unique biphasic development cycle. C. trachomatis …

Sequencing bacterial genomes from DNA isolated directly from clinical samples offers the
promise of rapid and precise acquisition of informative genetic information. In the case of …

Chlamydia trachomatis and Chlamydia (Chlamydophila) pneumoniae are important human
pathogens with significant socio-economic and medical impact. The development of an …