Abstract Information on gene alterations associated to poorly differentiated (PDTC) and
anaplastic thyroid carcinomas (ATC) is scarce. Using human cancer cell lines as a tool for …

The molecular profiling of tumour samples is elucidating the genetic alterations involved in
ATC development, and new preclinical models are under study to define innovative …

Anaplastic (ATC) and poorly differentiated thyroid cancer (PDTC) are very aggressive
cancers whose histological diagnosis is not always straightforward. Clinical, pathological …

Little is known about the genetic mechanisms behind the genesis of anaplastic thyroid
carcinoma. This is among the most virulent of all human malignancies, and it is believed to …

Little is known about the genetic mechanisms of anaplastic thyroid cancer (ATC). This is the
most virulent of all human malignancies, and it is believed to result from transformation of …

Background Papillary thyroid cancer (PTC) is the most common thyroid carcinoma and
exhibits an almost uniformly good prognosis, while anaplastic thyroid cancer (ATC) is less …

Background: Anaplastic thyroid carcinomas (ATCs) are among the most lethal malignancies,
for which there is no effective treatment. Objective: In the present study, we aimed to …

Background: Anaplastic thyroid carcinoma (ATC) accounts for only 3% of thyroid cancers,
yet strikingly, it accounts for almost 40% of thyroid cancer deaths. Currently, no effective …

Foci of papillary or follicular thyroid carcinoma are frequently noted in thyroidectomy
specimens of anaplastic thyroid carcinoma (ATC). However, whether ATCs evolve from …

BACKGROUND. Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer
(ATC) are rare and frequently lethal tumors that so far have not been subjected to …