We investigated the relationship between ErbB-2 and HLA in order to clarify the clinical and
genetic factors related to Japanese patients with lung cancer. Thirty-nine of the 73 lung …

AbstractPurpose: To investigate differences in HLA status among lung cancer patients,
patients with hematological malignancies, and healthy controls in order to determine the …

We determined c-erbB-2 protein level in serum of 86 primary lung cancer patients (78 non-
small cell lung carcinomas (NSCLC), 3 small cell carcinomas, 5 not histologically defined) …

The levels of ErbB-2 protein in serum samples from patients with breast cancer, other
various malignant tumors, and benign diseases were determined using the sandwich EIA for …

ErB-2 protein levels in breast cancer tissue extracts were determined by an enzyme immuno
assay (ErbB-2 EIA" Nichirei") using anti-c-erbB-2 monoclonal antibodies, and compared with …

Serum levels of c-erb B-2 protein were measured by an enzyme immunoassay in 64 patients
with lung adenocarcinoma. Immunohistochemical staining was performed in 40 of these …

Serum messenger RNA (mRNA) is an emerging prognostic tool for noninvasive malignant
disease prognosis, and to study serum mRNA may have importance in the prognosis and …

Only the kinase domain of ERBB4 has been analyzed in East Asian populations, but a
recent large-scale mutation analysis has indicated a higher incidence of mutations in the …

Abstract Background Human Epidermal Growth Factor Receptor 2 (HER-2; also known as
erbB-2 or neu), a proto-oncogene of the receptor tyrosine kinase superfamily, has been …

We studied non-small cell lung cancers (NSCLC) from 60 patients for abnormalities in the c-
erbB-2 gene. Eleven human lung cancer cell lines, including four derived from small cell …