Systems medicine: the future of medical genomics and healthcare
High-throughput technologies for DNA sequencing and for analyses of transcriptomes,
proteomes and metabolomes have provided the foundations for deciphering the structure …
proteomes and metabolomes have provided the foundations for deciphering the structure …
Systems biology and the future of medicine
J Loscalzo, AL Barabasi - Wiley Interdisciplinary Reviews …, 2011 - Wiley Online Library
Contemporary views of human disease are based on simple correlation between clinical
syndromes and pathological analysis dating from the late 19th century. Although this …
syndromes and pathological analysis dating from the late 19th century. Although this …
Systems medicine: the application of systems biology approaches for modern medical research and drug development
D Ayers, PJ Day - Molecular Biology International, 2015 - Wiley Online Library
The exponential development of highly advanced scientific and medical research
technologies throughout the past 30 years has arrived to the point where the high number of …
technologies throughout the past 30 years has arrived to the point where the high number of …
Systems medicine: evolution of systems biology from bench to bedside
High‐throughput experimental techniques for generating genomes, transcriptomes,
proteomes, metabolomes, and interactomes have provided unprecedented opportunities to …
proteomes, metabolomes, and interactomes have provided unprecedented opportunities to …
Systems approaches to biology and disease enable translational systems medicine
The development and application of systems strategies to biology and disease are
transforming medical research and clinical practice in an unprecedented rate. In the …
transforming medical research and clinical practice in an unprecedented rate. In the …
Whither systems medicine?
R Apweiler, T Beissbarth, MR Berthold… - … & molecular medicine, 2018 - nature.com
New technologies to generate, store and retrieve medical and research data are inducing a
rapid change in clinical and translational research and health care. Systems medicine is the …
rapid change in clinical and translational research and health care. Systems medicine is the …
Systems biology: its practice and challenges
A Aderem - Cell, 2005 - cell.com
Systems biology is a comprehensive quantitative analysis of the manner in which all the
components of a biological system interact functionally over time. Such an analysis is …
components of a biological system interact functionally over time. Such an analysis is …
Systems biology: personalized medicine for the future?
Systems biology is actively transforming the field of modern health care from symptom-
based disease diagnosis and treatment to precision medicine in which patients are treated …
based disease diagnosis and treatment to precision medicine in which patients are treated …
The art and practice of systems biology in medicine: mapping patterns of relationships
J Van der Greef, S Martin, P Juhasz… - Journal of proteome …, 2007 - ACS Publications
Systems biology has developed in recent years from a technology-driven enterprise to a
new strategic tool in Life Sciences, particularly for innovative drug discovery and drug …
new strategic tool in Life Sciences, particularly for innovative drug discovery and drug …
Enabling multiscale modeling in systems medicine
Systems medicine is an interdisciplinary approach that integrates data from basic research
and clinical practice to improve our understanding and treatment of diseases. Systems …
and clinical practice to improve our understanding and treatment of diseases. Systems …