The incidence of osteoarthritis (OA) has been expected to increase due to an aging
population, as well as an increased incidence of intra-articular (osteo-) chondral damage …

Objective Synovial inflammation is one of the most characteristic events in different types of
arthritis, including Osteoarthritis (OA). Emerging evidence also suggests the involvement of …

Mass spectrometry imaging (MSI) is a powerful technique enabling the visualization of the
spatial distribution of different molecules in tissue biopsies with different pathologies …

Objective The aim of this study was to carry out a targeted phospholipidomic analysis on
synovial fluid (SF) from patients with different grades of osteoarthritis (OA) and controls, in …

Osteoarthritis (OA) is one of the most common musculoskeletal diseases, characterized by
the progressive deterioration of articular cartilage. Although the disease has been well …

Osteoarthritis (OA) is a prevalent joint disease that can be exacerbated by lipid metabolism
disorders. The intra-articular fat pad (IFP) has emerged as an active participant in the …

Background Infrapatellar fat pad (IFP) has recently emerged as a potential source of
inflammation in knee arthropathies. It has been proposed to be one source of …

Osteoarthritis (OA) is a multifactorial pathology and comprises a wide range of distinct
phenotypes. In this context, the characterization of the different molecular profiles associated …

Objective Information about the distribution of proteins and the modulation that they undergo
in the different phases of rheumatic pathologies is essential to understanding the …

A fast and robust method for lipid profiling utilizing liquid chromatography coupled with mass
spectrometry has been demonstrated and validated for the analysis of human plasma. This …