Direct Oral anticoagulants for stroke prevention in special populations: beyond the clinical trials

A Carbone, R Bottino, A D'Andrea, V Russo - Biomedicines, 2023 - mdpi.com
Currently, direct oral anticoagulants (DOACs) are the first-line anticoagulant strategy in
patients with non-valvular atrial fibrillation (NVAF). They are characterized by a more …

Direct oral anticoagulants for the prevention of stroke in patients with nonvalvular atrial fibrillation: understanding differences and similarities

PP Dobesh, J Fanikos - Drugs, 2015 - Springer
The presence of atrial fibrillation (AF), the most common sustained cardiac arrhythmia,
significantly increases the risk for stroke. Current guidelines recommend that the vitamin K …

Direct oral anticoagulants for stroke prevention in atrial fibrillation: treatment outcomes and dosing in special populations

ZA Stacy, SK Richter - Therapeutic Advances in …, 2018 - journals.sagepub.com
Background: To review data from the pivotal phase III trials evaluating the efficacy and safety
of direct oral anticoagulants (DOACs) versus warfarin for stroke prevention in patients with …

Efficacy and safety of direct oral anticoagulants in patients with atrial fibrillation and high thromboembolic risk. A systematic review

D Acanfora, MM Ciccone, P Scicchitano… - Frontiers in …, 2019 - frontiersin.org
Background: The aim of the study was to evaluate the efficacy and safety of direct oral
anticoagulants (DOACs) in a subgroup of patients with atrial fibrillation (AF), CHADS2 …

Direct oral anticoagulants: key considerations for use to prevent stroke in patients with nonvalvular atrial fibrillation

J Ment - Vascular health and risk management, 2015 - Taylor & Francis
Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide. Strokes that occur
as a complication of AF are usually more severe and associated with a higher disability or …

Direct-acting oral anticoagulants in atrial fibrillation: what's new in the literature

F Ferrari, AD da Silveira, VM Martins… - Cardiology in …, 2021 - journals.lww.com
Atrial fibrillation (AF) is considered the most common sustained cardiac arrhythmia, and it is
associated with a significant risk of adverse events, especially ischemic stroke. Oral …

Clinical trials with direct oral anticoagulants for stroke prevention in atrial fibrillation: how representative are they for real life patients?

S Desmaele, S Steurbaut, P Cornu, R Brouns… - European journal of …, 2016 - Springer
Purpose To identify the proportion of real-life patients with atrial fibrillation (AF) eligible for
direct oral anticoagulant (DOAC) therapy, based on the inclusion and exclusion criteria used …

Use of direct oral anticoagulants in patients with atrial fibrillation and valvular heart lesions

L Di Biase - Journal of the American Heart Association, 2016 - Am Heart Assoc
Atrial fibrillation (AF) is the most common cardiac arrhythmia. It was estimated to affect up to
6.1 million Americans in 2010, and since AF is more common with increasing age, it is …

[HTML][HTML] Clinical discussions in antithrombotic therapy management in patients with atrial fibrillation: a delphi consensus panel

N Mumoli, C Amellone, G Antonelli, G Augello, C Cloro… - CJC open, 2020 - Elsevier
Background In recent years, direct-acting oral anticoagulants (DOACs) have entered clinical
practice for stroke prevention in non-valvular atrial fibrillation or prevention and treatment of …

Comparative Effectiveness and Safety of Direct Oral Anticoagulants in Low Body Weight Patients with Atrial Fibrillation: A Systematic Review and Meta-analysis

MN Elshafei, M Salem, A El-Bardissy… - … Drugs and Therapy, 2024 - Springer
Introduction Direct oral anticoagulant (DOAC) agents are established as the anticoagulation
strategy of choice for a variety of clinical risks. Despite this, uncertainty still exists with regard …