Vasoactive neuropeptides including substance P and calcitonin gene-related peptide
(CGRP) are localised in sensory nerves which innervate blood vessels. These are the major …

This review examines our current understanding of the roles of some of the best known
neuropeptides that have played major roles in our combined research programmes …

The term 'neurogenic inflammation'is commonly used, especially with respect to the role of
sensory nerves within inflammatory disease. However, despite over a century of research …

Cross‐talk between the nervous, endocrine and immune systems exists via regulator
molecules, such as neuropeptides, hormones and cytokines. A number of neuropeptides …

The vascular effects of endogenous substances can be easily studied in the skin. Early in
this century, vasoregulation was shown to be dependent on innervation. Peptidergic …

The aim of this article is to furnish a brief review of the role played by neurokinins in the
inflammatory process. Further attention is given to the mechanisms, as well as to the …

The cutaneous nervous system recently has been demonstrated to interact with multiple
target cells in the skin and to mediate actions important in inflammatory conditions …

Calcitonin gene-related peptide (CGRP), but not substance P (SP), was found to inhibit
edema-promoting actions of inflammatory mediators (histamine, leukotrine B 4, 5 …

Promising recent developments in the therapeutic value of neuropeptide antagonists have
generated renewed importance in understanding the functional role of neuropeptides in …

Inflammation, the proess by which animal organisms combat noxious stimuli, is a complex
cascade of events leading to homeostasis. Uncontrolled inflammation is undesirable …